Twitching on only one side or a portion of the body like an arm or leg. However, in general, febrile seizures are harmless. symptoms include vision problems like flashing lights or blind spots in one eye. What are the important side effects of Depakote (valproic acid)?Depakote (valproic acid) side effects list for healthcare professionals feet, arms, hands, or face, nausea, vomiting, and dizziness. Antiepileptic medications like Depakote have been associated with an increased risk of suicidal thinking and behavior. The list is not exhaustive, since new interactions are continuously being reported.Serum levels of carbamazepine (CBZ) decreased 17% while that of carbamazepine-10,11epoxide (CBZ-E) increased by 45% upon co-administration of valproate and CBZ to epileptic patients.Valproate displaces diazepam from its plasma albumin binding sites and inhibits its metabolism. None of these are typically serious, and may even disappear as the body gets used to the drug. It is estimated that one in every 25 children will have at least one febrile seizure. Febrile seizures Symptoms of bipolar disorder include mood changes and manic and depressive episodes. Additional tests usually are required to diagnose migraine from other types of headaches, diseases, or other medical problems. Seizure symptoms include unconsciousness, convulsions, and muscle rigidity.Epilepsy is a brain disorder in which the person has seizures. Untreated migraine attacks usually last from 4 to 72 hours, but may last for weeks. Depakote and Depakene can cause serious side effects, including: 1.Serious liver damage that can cause death, especially in children younger than 2 years old. Less commonly, a febrile seizure may only affect one side of the body.Bipolar disorder, or manic-depressive illness, is a disorder that causes unusual and extreme mood changes. Migraine "Types of Seizures." REFERENCES: CDC. Treatment, management, and prevention Both migraines and strokes can can cause severe head pain (migraine pain Epilepsy Thought disturbances If a patient becomes hypoglycemic during therapy, aggressive treatment with oral glucose and subsequent monitoring by a clinician is recommended. During the trials, four people taking a medication committed suicide, but none on a placebo did. This is compared to a rate of 5% for the 81 placebo patients.Including the long term extension study, the adverse reactions reported as the primary reason for discontinuation by ≥ 1% of 248 valproate-treated patients were:Table 5 includes those adverse reactions reported for patients in the placebo-controlled trials where the incidence rate in the Depakote-treated group was greater than 5% and was greater than that for placebo patients.The following additional adverse reactions were reported by greater than 1% but not more than 5% of the 202 Depakote-treated patients in the controlled clinical trials:The following adverse reactions have been identified during post approval use of Depakote. Abbott Pharmaceutical, Abbott Park, IL. Treatment for bipolar disorder in children and teenagers incorporates psychotherapy and medications.You are encouraged to report negative side effects of prescription drugs to the FDA. symptoms that include one or more seizures. Oral route (Tablet, Delayed Release; Capsule, Delayed Release; Tablet, Extended Release)Hepatotoxicity (some cases fatal), usually occurring during the first 6 months of treatment, has been reported in patients receiving valproate and its derivatives. Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study. illegal drug abuse, drug reactions, a severe chemical imbalance in the blood, or There is evidence that Depakote may lead to pancreatitis, or inflammation of the pancreas. cause the other.Headaches are the most common reason why a person goes to the doctor or other healthcare professional for treatment.