Although this is rare, it may occur more often in patients who are allergic to aspirin or to any of the nonsteroidal anti-inflammatory drugs (NSAIDs). The potential effects of diclofenac sodium topical solution on skin response to ultraviolet damage in humans are not known.Avoid contact of diclofenac sodium topical solution with eyes and mucosa. Therefore, do not use combination therapy with diclofenac sodium topical solution and an oral NSAID unless the benefit outweighs the risk and conduct periodic laboratory evaluations.Instruct patients that before applying sunscreen, insect repellant, lotion, moisturizer, cosmetics, or other topical medication to the same skin surface of the knee treated with diclofenac sodium topical solution, they must wait until the treated area is completely dry.Pregnancy Category C prior to 30 weeks gestation; Category D starting 30 weeks gestation.There are no adequate and well-controlled studies of diclofenac sodium topical solution in pregnant women. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID).Diclofenac is available only with your doctor's prescription.In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Meaningful elevations of ALT and/or AST occurred in about 4% of the 3,700 patients and included marked elevations (>8 times the ULN) in about 1% of the 3,700 patients. Based on clinical trial data and postmarketing experiences, monitor transaminases within 4 to 8 weeks after initiating treatment with diclofenac. Diclofenac gel is a nonsteroidal anti-inflammatory drug that is used to treat actinic keratosis. You can opt out at any time or find out more by reading our But if you use too much and get any side effects, tell your doctor straight awayDo not take diclofenac with similar painkillers - like Diclofenac, aspirin, ibuprofen and naproxen all belong to the same group of medicines called NSAIDs are also used in medicines you can buy from pharmacies - for example, cough and cold remedies. Talk with the doctor. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. Use the gel twice daily. Discontinuation of NSAID therapy is usually followed by recovery to the pretreatment state.No information is available from controlled clinical studies regarding the use of diclofenac sodium topical solution in patients with advanced renal disease. If you have any other skin condition - eczema, for example. Keep away from sparks or open flame.Aloe Barbadensis Leaf Extract, Bisabolol, Carbomer, Caprylyl Glycol, Cetearyl Alcohol, Ceteareth-20, Green Tea (Camellia Sinensis) Leaf Extract, Glycerin, Methylisothiazolinone, PEG-8, Polyglyceryl-3 Oleate, Triethanolamine, WaterCall toll-free 1-888-452-9975 or visit us at www.sirclelabs.comManufactured for: Sircle Laboratories, LLC, Madison, MS 39110Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F) [See USP Controlled Room Temperature].Manufactured for: Sircle Laboratories, LLC, Madison, MS 39110The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Consider this interaction in patients taking NSAIDs concomitantly with ACE-inhibitors.Clinical studies, as well as postmarketing observations, have shown that NSAIDs can reduce the natriuretic effect of furosemide and thiazides in some patients. Tell your doctor if you're taking:It's not possible to say that complementary medicines or herbal remedies are safe to take with diclofenac.They're not tested in the same way as prescription medicines or medicines sold in pharmacies. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate there frequency or establish a causal relationship to drug exposure.Drug interactions with the use of diclofenac sodium topical solution have not been studied. Carefully monitor patients receiving diclofenac sodium topical solution who may be adversely affected by alteration in platelet function, such as those with coagulation disorders or patients receiving anticoagulants.Because serious GI tract ulcerations and bleeding can occur without warning symptoms in patients taking NSAIDs, monitor patients for signs or symptoms of GI bleeding. We comply with the HONcode standard for trustworthy health information - Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events .NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. Spread diclofenac sodium topical solution evenly around front, back and sides of the knee. If these effects occur, get emergency help at once.It is important to tell your doctor if you are pregnant or planning to become pregnant before using diclofenac. Repeat this procedure until 40 drops have been applied and the knee is completely covered with solution.To treat the other knee, if symptomatic, repeat the procedure.Application of diclofenac sodium topical solution in an amount exceeding or less than the recommended dose has not been studied and is therefore not recommended.Diclofenac sodium topical solution is contraindicated in patients with a known hypersensitivity to diclofenac sodium or any other component of diclofenac sodium topical solution.Diclofenac sodium topical solution is contraindicated in patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Contained in diclofenac sodium topical solution and COX-2 selective and nonselective orally administered NSAIDs including. The manufacturer 's information leaflet supplied with your doctor if you are in the setting of artery... 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