Blomström-Lundqvist C, Scheinman MM, Aliot EM. Do not prescribe clarithromycin in people: With known hypersensitivity. Robinson K, Frenneaux MP, Stockins B, Karatasakis G, Poloniecki JD, McKenna WJ. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. Electrical storm in patients with transvenous implantable cardioverter-defibrillators: incidence, management and prognostic implications.  et al. Treating electrical storm: sympathetic blockade versus advanced cardiac life support-guided therapy. Hohnloser SH, Dorian P, Roberts R. Insomnia, memory disturbances, and delirium also have been reported.Fatal complications such as pulmonary fibrosis, cirrhosis, and bradycardia leading to cardiac arrest have been reported.Conversion rates with amiodarone have never been superior, and conversion occurs faster with other antiarrythmic drugs.In the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT), 1310 patients with ischemic cardiomyopathy and New York Heart Association (NYHA) class II or III CHF were randomized to receive ICD, placebo, or amiodarone.Amiodarone should be used judiciously (with close follow-up) in patients likely to derive the most benefit, namely those with AF and left ventricular dysfunction, those with acute sustained ventricular arrythmias, those about to undergo cardiac surgery, and those with ICDs and symptomatic shocks.© 2020 American Medical Association. Rosenbaum MB, Chiale PA, Halpern MS. Maintenance of sinus rhythm in patients with atrial fibrillation: an AFFIRM substudy of the first antiarrhythmic drug. Kochiadakis GE, Igoumenidis NE, Marketou ME, Kaleboubas MD, Simantirakis EN, Vardas PE. Letelier LM, Udol K, Ena J, Weaver B, Guyatt GH. Multicenter Automatic Defibrillator Implantation Trial Investigators. All possible dosages and forms may not be included here. Low-dose amiodarone for maintenance of sinus rhythm after cardioversion of atrial fibrillation or flutter. Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy. Amiodarone hydrochloride (marketed as Cordarone) information. Our website uses cookies to enhance your experience. This can be life-threatening. These drugs are often used to treat similar conditions.Amiodarone treats and prevents abnormal heartbeats by working inside cells to control muscle contractions in the heart. Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations. Ott MC, Khoor A, Leventhal JP, Paterick TE, Burger CD. et al. Chun SH, Sager PT, Stevenson WG, Nademanee K, Middlekauff HR, Singh BN. Amiodarone for long-term management of patients with hypertrophic cardiomyopathy. ACC/AHA/ESC Guidelines for the Management of Patients With Supraventricular Arrhythmias—executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias). Canadian Trial of Atrial Fibrillation Investigators. et al. et al. Jung W, Manz M, Pizzulli L, Pfeiffer D, Luderitz B. Potential benefit from implantable cardioverter-defibrillator therapy in patients with and without heart failure. Freemantle N, Cleland J, Young P, Mason J, Harrison J. beta Blockade after myocardial infarction: systematic review and meta regression analysis. (5) Amiodarone in conjunction with β-blockers is effective for electrical storm.  et al. et al. Evolution and revolution in drug labeling: regulation of antiarrhythmic drugs by the Food and Drug Administration 1962-1996. Pelosi F Jr, Oral H, Kim MH. In general, as you age, your organs, such as your liver, kidneys, and heart, don’t work as well as they once did. Drug Interactions Clinical efficacy of amiodarone as an antiarrhythmic agent. The Atakr Multicenter Investigators Group. Villain E, Vetter VL, Garcia JM, Herre J, Cifarelli A, Garson A Jr. Low-dose amiodarone for atrial fibrillation.  et al. Keep out of reach of children. Mitchell LB, Exner DV, Wyse DG. Contraindications for amiodarone include being allergic to it, iodine, or any of the inactive components used to make the medication. Ventricular fibrillation after intravenous amiodarone in Wolff-Parkinson-White syndrome with atrial fibrillation. Some may be severe, requiring dose reduction or discontinuation of therapy of... 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