This syringe type has the highest breakout force after any tested park time, and the breakout force increases substantially with park time—for example at 0.25 hours (15 minutes) park time the breakout force is about 6 N but at 24 hours the breakout force is about 18 N—three times as great.The bilayer syringe samples represented by the data points Example 17 is carried out comparably to Example 16, except that in addition to the above types of samples, all represented by data points having the same reference numbers in FIG. An average dissolution rate for protracted storage times was then calculated by extrapolating the data obtained according to the Protocol for Determining Average Dissolution Rate. 4 shows similar results again, and for the plasma treatment only samples represented by the points The working examples thus show several different types of plasma treatments, with and without deposition of a PECVD coating, improving the breakout force and the rate of increase of breakout force with park time in a molded plastic syringe. 3 ml of each test solution is placed in borosilicate glass 5 ml pharmaceutical vials and SiOThe Protocol for Determining Average Dissolution Rate Si content is used to monitor the rate of glass dissolution, except as modified here. U.S. 1 is an exploded longitudinal section of a syringe, plunger, and cap assembly of a prefilled syringe.FIG. The best representative pieces for each specimen were selected for testing. Standard volumes can also be defined using different standard temperatures and pressures, and still be within the scope of the present disclosure and claims. The substrate surface can be part or all of the inner or interior surface of a vessel having at least one opening and an inner or interior surface.A “hydrophobic layer” in the context of the present invention means that the coating or layer lowers the wetting tension of a surface coated with the coating or layer, compared to the corresponding uncoated surface. © 2004-2020 FreePatentsOnline.com. For example, in the working examples the flow rates are expressed as standard cubic centimeters per minute, abbreviated as sccm. The digestion step is carried out to quantitatively remove the silicon coatings from the vessel wall into the KOH solution. The word “comprising” does not exclude other elements or steps, and the indefinite article “a” or “an” does not exclude a plurality unless indicated otherwise. Feel free to send suggestions. Provisional Appl. Its use is analogous to use in the context of a syringe and its plunger tip, and the measurement of these forces for a vessel and its closure are contemplated to be analogous to the measurement of these forces for a syringe, except that at least in most cases no liquid is ejected from a vessel when advancing the closure to a seated position.“Slidably” means that the plunger tip, closure, or other removable part is permitted to slide in a syringe or other vessel.The present invention will now be described more fully, with reference to the accompanying drawings, in which several embodiments are shown. The present hydrophobic layers are primarily defined by their hydrophobicity and the process conditions providing hydrophobicityThe values of w, x, y, and z as applicable to the empirical composition Si“Wetting tension” is a specific measure for the hydrophobicity or hydrophilicity of a surface. The test solutions used for dissolution contained either 0.02 or 0.2 wt. 3, then tested for FThe following guide is provided to assist interpretation of the test results represented in FIG. Jones, Joseph A. 20, 2012; 61/654,612, filed Jun. These European patent applications describe apparatus, vessels, precursors, coatings or layers and methods (in particular coating methods and test methods for examining the coatings or layers) which can generally be used in performing the present invention, unless stated otherwise herein. The standard volume of a charge or other fixed amount of gas is the volume the fixed amount of the gas would occupy at a standard temperature and pressure (without regard to the actual temperature and pressure of delivery). The fluid to be dispensed can be any of the inhalation anesthetics, injectable drugs, liquid drugs (non-injectable), drug classes, diagnostic test materials, or other materials recited in the specification or claims.Many other embodiments of the present invention are expressly contemplated, as recited in the claims.FIG. It is believed that the use of a higher power level causes higher cross-link density of the primer coating or layer.A preliminary study was conducted to compare the relative amounts of free (i.e. That way, every time you open a new tab you review 2-3-5 cards before doing something else, mixing these tiny chunks of flashcards reviewing through the day, which should also improve memory-retention as interleaving comes into play. 24, 2009; 61/234,505, filed Aug. 17, 2009; 61/261,321, filed Nov. 14, 2009; 61/263,289, filed Nov. 20, 2009; 61/285,813, filed Dec. 11, 2009; 61/298,159, filed Jan. 25, 2010; 61/299,888, filed Jan. 29, 2010; 61/318,197, filed Mar. The results of this calculation are:Based on this calculation, the OMCTS protective layer needs to be about 2.5 times thicker—resulting in dissolution of 33945 ppb versus the 14,371 ppb representing the entire mass of coating tested—to achieve a 3-year calculated shelf life.The results of Comparative Example 8 and Example 9 above can be compared as follows, where the “primer coating or layer” is the coating of SiOThis data shows that the silicon dissolution rate of SiOAnother comparison is shown by the data in Table 5 from several different experiments carried out under similar accelerated dissolution conditions.An experiment similar to Example 9 was carried out, modified as indicated in this example and in Table 3 (where the results are tabulated).