Opioids will reduce the absorption of clopidogrel if used together. Uses/Indications Decrease the risk for the development of blood clots in instances of feline cardiomyopathies, pulmonary hypertension, and … It's given to pets to prevent the formation of blood clots in the bloodstream due to injuries. Thank you for your question. 4,5 In cats, a total dose of 18.75 mg (one-quarter of a 75-mg tablet) PO once a day has been shown to reduce platelet aggregation and prolong oral mucosal bleeding time. CLOPIDOGREL BISULFATE (for veterinary information only) BRAND NAME: PLAVIX . Yes, but your DVM should be made aware of the additional dose. Protect from moisture. Brainard B M, Kleine S A, Papich M G, Budsberg S C (2010) Pharmacodynamic and pharmacokinetic evaluation of clopidogrel and the carboxylic acid metabolite SR 26334 in healthy dogs. However, if it is almost time for the next dose, skip the missed dose and resume the normal dosing schedule. This drug should not be given to Dogs and cats, just like people, can have trouble with the ol’ ticker. Clopidogrel is an antagonist of the P2Y12 receptor which is an ADP receptor found on the surface of the platelet. Dosage is not based on weight. The following list contains some of the key side effects that may occur while taking clopidogrel. It's given to pets to prevent the formation of blood clots in the bloodstream due to injuries. All rights reserved. This content is informational/educational and is not intended to treat or diagnose any disease or patient. Do not give this medication to a person.Federal law restricts this drug to use by or on the order of a licensed veterinarian.Clopidogrel decreases the ability to form blood clots. Clopidogrel works on platelets, which are the blood cells that are responsible for clot formation. Be the first to hear about new products, latest news, and more. Food & Nutrition If your doctor prescribes Plavix, when filling your prescription, be sure to call ahead to make sure your pharmacy carries it.There are other drugs available to treat your condition. Clopidogrel is an anticoagulant, antiplatelet medication for both cats and dogs. An ACE inhibitor and generic option of Lotensin, this medication can help manage your pet's congestive heart failure or hypertension. Examples of these drugs include:Taking an opioid medication with clopidogrel can delay the absorption and reduce the amount of clopidogrel in your body, making it less effective. A class of drugs is a group of medications that work in a similar way. Other drugs that may increase clotting time include non-steroidal anti-inflammatory drugs, and warfarin/coumarin anticoagulants. And, just like with people, they need to be treated. You and your veterinarian will need to weigh the benefits of drugs that increase clotting time with the possible risks associated with bleeding.Clopidogrel may slow the metabolism of non-steroidal anti-inflammatory drugs, phenytoin, toresemide, and warfarin.If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the If you or someone else has accidentally ingested this medication call the Different strengths or dosage forms of clopidogrel may have different storage requirements. Recent publications include portions of The Pill Book Guide to Medication for Your Dog and Cat, and most recently Understanding Equine Medications published by the Bloodhorse.Dr. 75 mg once daily orally without a loading dose [see Clinical Pharmacology (12.3) and Clinical Studies (14.2)]. Do not stop giving your pet Clopidogrel without consulting your veterinarian.Side effects of Clopidogrel may include an increased risk of bleeding, vomiting, and anorexia. Lymphoma Treatment Includes Nutritional Therapy for Dogs and Cats.