Chlorzoxazone: CYP2E1 Inhibitors (Strong) may increase the serum concentration of Chlorzoxazone. Phenytoin dose adjustment will likely be necessary when starting and/or stopping concurrent disulfiram. Central nervous system: Bitter taste (garlic), drowsiness, fatigue, headache, metallic taste, peripheral neuritis, peripheral neuropathy, polyneuropathy, psychosisDermatologic: Acneiform eruption, allergic dermatitis, skin rashHepatic: Cholestatic hepatitis, fulminant hepatitis, hepatic failure (multiple case reports)Disulfiram should never be administered to a patient when he is in a state of alcohol intoxication, or without his full knowledge. Another brand of sildenafil is Revatio, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Disulfiram occurs as a white to off-white, odorless, and almost tasteless powder, soluble in water to the extent of about 20 mg in 100 mL, and in alcohol to the extent of about 3.8 g in 100 mL. Specifically, disulfiram may produce severe intolerance to the alcohol contained in the dronabinol oral solution. Severe reactions may involve respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, seizure and death. High acetaldehyde causes uncomfortable symptoms including flushing, throbbing in head and neck, nausea, vomiting, diaphoresis, thirst, palpitations, chest pain, dyspnea, hyperventilation, tachycardia, syncope, weakness, blurred vision, confusion, vertigo, and hypotension. Sweep spilled substance into covered containers. Monitor for increased effects of tizanidine, including adverse reactions.Vitamin K Antagonists (eg, warfarin): Disulfiram may increase the serum concentration of Vitamin K Antagonists. The maximum recommended daily dose is 500 milligrams.Use this medication regularly to get the most benefit from it. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. Available for Android and iOS devices. Management: Avoid these combinations when possible. Viagra relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body.Viagra is used to treat erectile dysfunction (impotence) in men. CloZAPine: CYP1A2 Inhibitors (Weak) may increase the serum concentration of CloZAPine. Disulfiram neuropathy: two cases of distal axonopathy. Excipient information presented when available (limited, particularly for generics); consult specific product labeling.Disulfiram is a thiuram derivative which blocks the oxidation of alcohol at the acetaldehyde stage. The physician should instruct relatives accordingly.• Disulfiram reaction: Ingesting alcohol, even in small amounts, during treatment with disulfiram may result in flushing, throbbing in head and neck, nausea, copious vomiting, respiratory difficulty, diaphoresis, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision and confusion. A disulfiram-like reaction may occur. https://www.webmd.com/drugs/2/drug-1446/disulfiram-oral/details When taken concomitantly with alcohol, there is an increase in serum acetaldehyde levels. Dronabinol: Disulfiram may enhance the adverse/toxic effect of Dronabinol. Morning administration is preferred, but may be given at bedtime if sedation is experienced. 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