A doctor may not request for a liver function test, but may get a blood test done to check out the levels of the enzymes of the liver. (See Reference 3) However, the dosage of the medication will be low and should only be taken under supervision of a doctor. Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class that is primarily used in treatment of hypertension, congestive heart failure, and heart attacks and also in preventing renal and retinal complications of diabetes. I had another liver enzyme test done beg of Oct 2008 and now the ALT is up to 66. Oxycontin. // Leaf Group Lifestyle In the US, 1 in 4 people is suffering from high blood pressure. Oxycontin is a powerful pain reliever that works by having a controlled release of oxycodone into the bloodstream. The other liver enzymes that can be elevated are cholestatic enzymes, such as alpha phosphatase (ALP) and gamma glutamyl transferase (GGT) (See Reference 2) A person taking Lisinopril is at the risk of getting cholestatic jaundice when the liver enzymes are elevated in the body. Research suggests that 25–51% of people with elevated liver enzymes have this … These are known as the transaminases. Elevated blood pressure is something that people should take seriously. Karla has a doctorate in pharmacy from St. John's University and holds a pharmacy license for the state of New York. (See Reference 1) Hence, the benefits of using Lisinopril outweigh the side effects and possible liver problems caused by the medication. Mark Russo and Ira Jacobson in the January 2004 issue of the “Cleveland Clinic Journal of Medicine.” It is also used for the treatment of congestive heart failure. Beyond elevating liver enzymes, SSRIs can also cause hepatitis, leading to fatigue and severe abdominal pain. Bile is a yellow-green fluid produced by the liver and stored in the gall bladder. (See Reference 1) It has also been seen that Lisinopril can lead to liver problems. Sometimes lisinopril may elevate liver enzymes, but in those cases lisinopril should/will be discontinued. Hepatic side effects associated with the use of ACE inhibitors have included a rare syndrome that begins with cholestatic jaundice and progresses to fulminant hepatic necrosis and (sometimes) death. 1) Acetaminophen (Tylenol) Acetaminophen works well as a fever reducer and pain reliever but is one of the most common causes of medication-related liver failure. When that enzyme is inhibited, the blood vessels can relax and dilate, so that the pressure exerted by the blood on the walls of the arteries reduces. The other liver enzymes that can be elevated are cholestatic enzymes, such as alpha phosphatase (ALP) and gamma glutamyl transferase (GGT) (See Reference 2) A person taking Lisinopril is at the risk of getting cholestatic jaundice when the liver enzymes are elevated in the body. (See Reference 2) It has been seen that this kind of jaundice is more common in patients taking Lisinopril and having low levels of proteins. The most common cause of elevated liver enzymes is fatty liver disease. Damage to the liver by statin drugs causes an increased release of liver enzymes into the circulation, most commonly the enzymes aspartate aminotransferase or alanine aminotransferase, according to Drs. (See Reference 1) Elevated blood pressure can lead to heart failure, strokes and kidney failure. Oxycodone activates opioid receptors in the central nervous system resulting in pain relief. Aldosterone leads to the retention of sodium and water, which can elevate the blood pressure. Lisinopril is a prescription medication that belongs to class of medications called the angiotensin-converting enzyme inhibitors, or ACE inhibitors. She has also created patient handouts, PowerPoint presentations and journal clubs. How Long Does It Take For Lisinopril Cough To Go Away ? ALP and GGT are known as cholestatic liver enzymes. (See Reference 3) Usually, when a person is taking Lisinopril, it is recommended that he or she go for regular check ups to the doctor to ensure that the blood pressure is being maintained and also there are no associated problems from taking the medication.