Genetic Implication. Imipramine helps to elevate mood and eliminate or reduce other symptoms associated with depression. Imipramine is the only TCA used as temporary adjuvant treatment of enuresis in children >6 y. Its mode of action is unclear, however, it appears to sensitise tissues to the action of acetylcholine. Measure liquid forms carefully. In young adults and children over 1 year of age this medicine is used to:Ask your doctor if you have any questions about why this medicine has been prescribed for you. Some of the symptoms of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath.Do not take this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. Imipramine helps to elevate mood and eliminate or reduce other symptoms associated with depression. Serotonin and noradrenaline are known to be involved in regulating emotions, mood and behaviour, among other things. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. However, common side effects are typically similar to other tricyclic antidepressants and include sleepiness, dry mouth, and constipation. Name /bks_53161_deglins_md_disk/imipramine 02/14/2014 03:35PM Plate # 0-Composite pg 1 # 1 PDF Page #1 Canadian drug name. With a dose of 200 mg /day, a maximum of 29 μg/L imipramine and 35 μg/L desipramine has been measured in the mother’s milk ( Sovner 1979 ). Monitor your pet at home for serious side effects.Store the tablets and capsules at room temperature and protect from light. Serious side effects are rare.If any of the following happen, stop taking Pramin and tell your doctor immediately, or go to Accident and Emergency at the nearest hospital:These are rare yet serious side effects and may need urgent medical attention.Tell your doctor or pharmacist if you notice anything that is making you feel unwell. This is because the tablets do not dissolve properly in a dry mouth. If they are not available, follow their directions in contacting an emergency facility. They may differ from the information contained here.If you do not understand the instructions on the pack, ask your doctor or pharmacist for help.Your doctor may advise you to take a different dose. Pramin may cause drowsiness, dizziness or lightheadedness in some people. In depressive illness less serotonin and noradrenaline than normal is released from nerve cells in the brain.Imipramine works by prolonging the effects of serotonin and noradrenaline that have been released in the brain. It increases the resting tone of the lower oesophageal sphincter and has little, if any, effect on the motility of the colon or gallbladder.The active ingredient in Pramin is metoclopramide hydrochloride. It increases the capacity of the bladder to hold urine, reduces the need to pass urine and can help the child stay dry at night. Other side effects may include diarrhea, vomiting, or trouble urinating. It increases the tone and amplitude of gastric (especially antral) contractions, relaxes the pyloric sphincter and the duodenal bulb, and increases peristalsis of the duodenum and jejunum resulting in accelerated gastric emptying and intestinal transit. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.The side effects listed below are not experienced by everyone who takes this medication. Your veterinarian may monitor your pet to be sure that the medication is working. Give as directed by your veterinarian. Imipramine is an antidepressant medicine sometimes prescribed to treat bedwetting in children - what should you know about it?Imipramine hydrochloride is a type of medicine called a Imipramine works in depression by enhancing the activity of neurotransmitters called serotonin and noradrenaline in the brain.