Dosing Modifications Lopressor When converting patients on a continuous IV infusion of diltiazem to an oral dose of diltiazem, you can use the following equation: Oral dose (in mg per day) = [rate (mg/hr) x 3 + 3] x 10 ; When initially converting someone from an IV infusion of diltiazem to oral diltiazem it recommended that you start off using immediate release (IR) dosage formulations where the equivalent daily … 2002 lopressor-hct-dutoprol-metoprolol-hydrochlorothiazide-999423 ratio is used. IV: 1.25-5 mg q6hr; avoid IV administration in unstable heart failure or acute myocardial infarction. If transient worsening of heart failure occurs, consider treating with increased doses of diuretics, lowering the dose of TOPROL-XL or temporarily discontinuing it. /viewarticle/920470 All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. Atrial Fibrillation/Flutter or Supraventricular Tachycardia (Off-label) 2.5-5 mg IV q2-5min; not to exceed 15 mg over 10-15 minutes; maintenance: 25-100 mg PO q12hr. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. In patients with severe intolerance, treatment with metoprolol should be discontinued. In patients who tolerate full 15 mg dose, oral lopressor 50mg po q6h should be started 15 min after last IV dose x 48 hours. -------------------------------------------------------------------------------- Treatment in this early phase should begin with the intravenous administration of three bolus injections of 5 mg of metoprolol tartrate each; the injections should be given at approximately 2-minute intervals. generic drugs) are not considered. Dosages above 400 mg per day have not been studied. Individual plans may vary Individual plans may vary This website also contains material copyrighted by 3rd parties. In general, the maximum effect of any given dosage level will be apparent after 1 week of therapy. The infusion times were formulated to mimic the onset of an oral formulation. Prior to initiation of TOPROL-XL, stabilize the dose of other heart failure drug therapy. Do not freeze. 2001 May switch to oral dosing (50 to 100mg po q6h) after IV bolus therapy. Than if no adverse effects are observed the doses may be increased, if needed, to 50 mg and than to 100 mg (to take the desired effect). informational and educational purposes only. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. Drugs Diseases & Conditions 5 mg rapid IV q2min, up to 3 doses; then, 15 minutes after last IV, 50 mg PO q6hr for 48 hours; then 50-100 mg PO q12hr ; If full IV dose not tolerated: 25-50 mg PO q6hr after last IV ; Congestive Heart Failure Toprol XL. Double the dose every two weeks to the highest dosage level tolerated by the patient or up to 200 mg of TOPROL-XL. Calculation of equivalent doses of antihypertensive drugs : β-Blocker News Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Atrial fibrillation is the most common arrhythmia in patients visiting a primary care practice. Name /bks_53161_deglins_md_disk/metoprolol 02/17/2014 07:39AM Plate # 0-Composite pg 3 # 3 Canadian drug name. Supraventricular tachycardias(PAT, A-fib/flutter): 5 to 15 mg (usually 5 mg) over 2.5 min at 7.5min intervals-usually a high response rate. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvbG9wcmVzc29yLXRvcHJvbC14bC1tZXRvcHJvbG9sLTM0MjM2MA==