If you do not receive an email within 10 minutes, your email address may not be registered, Please enable scripts and reload this page. Twenty patients with mild chronic bronchial asthma (females and males between 45-69 years old) treated with single dose of 0.5 mg at 1 ml of salbutamol were investigated. Measurements of heart rate, blood pressure, peak expiratory flow rate (PEFR) and plasma concentration or glucose, potassium and non-esterified fatty acids-NEFA, and salbutamol plasma levels were recorded at the same time before and 2, 5, 15, 30, 60, 75, 90, 120, 180, 240, and 360 min after salbutamol injection. 123 ml min‐1). Please try after some time.Get new journal Tables of Contents sent right to your email inbox Unable to load your delegates due to an error Message: Salbutamol has rapid onset pharmacodynamics as a bronchodilator C. E. Sottas Paediatric Intensive Care Unit, Auckland Children's Hospital, Auckland, New Zealand By continuing to browse this site, you agree to its use of cookies as described in our I have read and accept the Wiley Online Library Terms and Conditions of UsePregnancy-Associated Changes in Pharmacokinetics: A Systematic Review, Intravenous salbutamol for childhood asthma: evidence-based medicine?, The influence of active secretion processes on intestinal absorption of salbutamol in the rat, European Journal of Pharmaceutics and Biopharmaceutics, Autotransfusion en cours de césarienne de sang contenant du salbutamol sans effets indésirables, Annales Françaises d'Anesthésie et de Réanimation, Determination of salbutamol enantiomers in human plasma and urine by chiral high-performance liquid chromatography, Journal of Chromatography B: Biomedical Sciences and Applications, PK/PD analysis of albuterol action: application to a comparative assessment of β2-adrenergic drugs, Studies of cyclodextrin inclusion complexes. The drug was well absorbed and 65 to 84 per cent of … Pharmacokinetics: Both S- and R-omeprazole are pro-drugs, which are converted within the parietal cell to the active proton pump inhibitor, which lacks a chiral centre. The item(s) has been successfully added to " The pulmonary absorption of salbutamol from a complex with 2-hydroxypropyl-β-cyclodextrin in rabbits, This article has been saved into your User Account, in the Favorites area, under the new folder Peak plasma levels of between 212 and 489 nm. For information on cookies and how you can disable them visit our You may be trying to access this site from a secured browser on the server. Despite a significantly higher price than racemic salbutamol, it offers no demonstrated clinical advantage. most commonly used drugs. Message: Overall there were only minor differences in salbutamol pharmacokinetics between control subjects and patients in premature labour.Please check your email for instructions on resetting your password. 301-223-2300 Your Email: 1 The pharmacokinetics of salbutamol and its sulphate conjugate were examined during intravenous and steady‐state oral administration in nine patients receiving the drug for the prevention or treatment of premature labour. Please try after some time.Your message has been successfully sent to your colleague.Some error has occurred while processing your request. Paediatric Intensive Care Unit, Auckland Children's Hospital, Auckland, New ZealandDepartment of Anaesthesiology, Auckland University, Auckland, New ZealandB. The probability of target attainment expectation in the study population was 0.45. Register Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Department of Psychiatry, University of Vienna, Austria.Use the link below to share a full-text version of this article with your friends and colleagues.