We targeted 5 medications with equal oral and intravenous bioavailability: fluconazole, levofloxacin, metronidazole, ranitidine, and amiodarone. Oral dosage forms of many drugs with high bioavailability result in … Oral dosing differs according to the disease state. IV Medication Ordered Oral/Tube Medication Administered Section 1 Pantoprazole IV, dose and frequency . Members of _ can log in with their society credentials belowMembers of _ can log in with their society credentials below For GERD, the dosage is 20 to 40 mg PO twice daily. Silverchair Information Systems This site uses cookies. IV to PO Conversion Table . Simply select your manager software from the list below and click on download. J Am Geriatr Soc. 2004 Jul-Aug;11(4):278-80. doi: 10.1197/jamia.M1531. Pantoprazole PO/TUBE, same dose and frequency . Oral: 150 mg twice daily; adjust dose or frequency as clinically indicated; doses of up to 6 g/day have been used . Oxford University Press is a department of the University of Oxford. There are no adequate and well-controlled studies with ranitidine in pregnant women; animal studies have not demonstrated a risk to the fetus. This site needs JavaScript to work properly. Taeho Oh, M.S., Kevin Rumsey, Jack Neistein, M.S., Thomas G. Francko, M.S. for oral (PO) and intravenous (IV) administration, will be automatically converted to esomeprazole. Parenteral ranitidine offers no therapeutic advantage over oral therapy if the gastrointestinal tract is intact and functioning.Research off-campus without worrying about access issues. By continuing to browse ASHP delegates meet remotely to adopt forward-looking policies It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwideFor full access to this pdf, sign in to an existing account, or purchase an annual subscription.Department of Pharmacy St. Francis Hospital 250 West 63rd Street Miami, FL 33141 During the second phase, the pharmacy staff reviewed 4301 profiles of patients receiving iv ranitidine over eight months. Don't already have an Oxford Academic account? In phase 1, iv ranitidine was inappropriate either partially or totally in 51 percent of the cases. After oral administration of 150 mg 3H-ranitidine, 96% of the dose was recovered, 26% in faeces and 70% in urine of which 35% was unchanged parent drug. Clipboard, Search History, and several other advanced features are temporarily unavailable. Name must be less than 100 characters hours. Intravenous to Oral Conversion Program Background: Many hospitals across the country, including several in the Providence Health System, have P&T approved programs whereby pharmacists automatically switch patients from IV to oral dosage forms of selected drugs if certain criteria are met. For more information view the A two-phase drug program concentrating on inappropriate use of intravenous ranitidine is described at a 612-bed university teaching hospital. I.V. We targeted 5 medications with equal oral and intravenous bioavailability: fluconazole, levofloxacin, metronidazole, ranitidine, and amiodarone. While many of the other antacids that are currently on the market do not work by this mechanism (and I, therefore, do not recommend their use), the other H2 blocker that is readily available by prescription and “over the counter” is Pepcid/famotidine. Please refer to the Intravenous to Oral Medication Conversion Program for further details. Document created: 02/08. ASHP Statement on the Use of Artificial Intelligence in Pharmacy : Continuous infusion for Zollinger-Ellison: 1 mg/kg/hour; measure gastric acid output at 4 hours, if >10 mEq or if patient is symptomatic, increase dose in increments of 0.5 mg/kg/hour; doses of up to 2.5 mg/kg/hour have been used Hemodialysis: Adjust dosing schedule so that dose coincides with the end of hemodialysis IVP: Ranitidine (usually 50 mg) should be diluted to a total of 20 mL with NS or D5W and administered over at least 5 minutes. We measured the total use of the targeted medications via each … Search for other works by this author on: 2017 Mar;49(1):31-37. doi: 10.3947/ic.2017.49.1.31. This site uses cookies. Search for other works by this author on: 2 To convert patients from ranitidine to famotidine, divde the ranitidine dose by 7.5… Educational memos were placed in 451 patient charts (11 percent) where conversion from iv to oral therapy was feasible; a favorable follow-up occurred in 275 cases (61 percent). : Continuous infusion for Zollinger-Ellison: 1 mg/kg/hour; measure gastric acid output at 4 hours, if >10 mEq or if patient is symptomatic, increase dose in increments of 0.5 mg/kg/hour; doses of up to 2.5 mg/kg/hour have been used . This recommendation is derived from adult clinical studies and pharmacokinetic data in pediatric patients. Unable to load your delegates due to an error doi: 10.1371/journal.pone.0183062. Cimetidine is not an anticholinergic agent. Epub 2018 Jun 17.PLoS One. ORAL:-Treatment dose: 150 mg orally 2 times a day OR 300 mg orally once a day after the evening meal or at bedtime-Maintenance dose: 150 mg orally once a day at bedtime-Duration of therapy: 8 weeks (treatment); up to 1 year (maintenance) PARENTERAL: IM or IV (bolus or intermittent infusion) Injection:-Usual dose: 50 mg IM or IV every 6 to 8 hours