Try to keep to the recommended guidelines of no more than 14 units of alcohol a week. Article date: August 2012. You can also buy a low-strength 10mg tablet from a pharmacy.Simvastatin can be taken by adults and children over the age of 10 years.Take simvastatin once a day in the evening. Azulfidine - Clinical Pharmacology Pharmacodynamics. Is it safe to take simvastatin for a long time? It is also used to decrease the risk of heart problems in those at high risk. However there's no firm evidence that taking CoQ10 at the same time as simvastatin will benefit your health. Tell your doctor or diabetes nurse if you find it harder to control your blood sugar.Statins all work in the same way, but they differ in how well they lower cholesterol.There are several other statin medicines for lowering your cholesterol, including:If you have a side effect with one statin, it may not happen with another. However, stopping simvastatin may cause your cholesterol to rise. For a full list see the leaflet inside your medicines packet.Simvastatin is not recommended in pregnancy and while breastfeeding.Talk to your doctor if you're planning to become pregnant. Common side effects include constipation, headaches, and nausea.Simvastatin has been used to explore whether statins have an effect on delaying on the onset and progression of Common side effects (>1% incidence) may include indigestion and eczema. It is taken by mouth. Molecular Formula: C 18 H 14 N 4 O 5 S Inactive ingredients: magnesium stearate, povidone, silica (colloidal anhydrous), starch (pregelatinized). Rare side effects include joint pain, memory loss, and muscle cramps.On 19 March 2010, the FDA issued another statement regarding simvastatin, saying it increases the risk of muscle injury (myopathy) when taken at high doses or at lower doses in combination with other drugs.Consuming large amounts of grapefruit juice increases serum levels of simvastatin by up to three-fold, increasing the risk of side effects.Simvastatin also interacts with other drugs, including some used to treat cardiovascular problems. They may recommend taking a different statin.Another very rare side effect can be memory loss. Simvastatin, marketed under the trade name Zocor among others, is a lipid-lowering medication. Will taking pravastatin increase my risk of diabetes? This is because statins can raise your blood sugar a little. Does it help to take supplements together with statins? If you stop taking simvastatin without starting a different treatment, your cholesterol level may rise again.You may have read negative stories about statins, but they're thought to be very safe, effective medicines.Statins are thought to have very few side effects. How does it compare with other medicines for high cholesterol? You won't get any withdrawal symptoms when you stop taking it.You may want to stop simvastatin if you think you're having side effects. Talk to your doctor first to see if it really is a side effect of People with very high cholesterol levels may be prescribed a higher dose of 80mg a day.The usual starting dose in children is 10mg each evening. Your doctor may decide to lower your dose or change your medicine. 10–15 % risk of major event in 10 years), max. prescribed a statin medicine. Simvastatin is a prodrug in which the 6-membered lactone ring of simvastatin is hydrolyzed in vivo to generate the beta,delta-dihydroxy acid, an active metabolite structurally similar to HMG-CoA (hydroxymethylglutaryl CoA). Simvastatin 10 mg tablets can be sold to the public to reduce risk of first coronary event in individuals at moderate risk of coronary heart disease (approx. This is because your body makes most cholesterol at night.Simvastatin doesn't upset the stomach, so you can take it with or without food.The usual dose for adults is between 10mg and 40mg once a day. The mode of action of sulfasalazine (SSZ) or its metabolites, 5-aminosalicylic acid (5-ASA) and sulfapyridine (SP), is still under investigation, but may be related to the anti-inflammatory … You may be able to stop taking simvastatin temporarily while you breastfeed.Some medicines don't mix well with simvastatin, including:If you're taking simvastatin and need to take one of these medicines, your doctor may:Talk to your doctor if you're thinking about starting St John's wort, as it will change how well simvastatin works.Tell your doctor and pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements.For the first 12 months on this medicine, you'll be offered a couple of routine tests to make sure your liver is working OK.Your cholesterol levels should drop noticeably within 4 weeks - if you take your medicine regularly, as prescribed.Usually, treatment with a statin such as simvastatin is for life.