It comes as an oral tablet. Taste Impairment 9. Other side effects include: syncope, edema, ataxia, confusion, diarrhea, hypotension, insomnia, sedated state, and tachycardia. Trazodone is considered safe and effective in animals when it is prescribed by a vet and used properly. Serious side effects do not occur when Trazodone is prescribed in low dosages. The increase in alpha-2 adrenoreceptor functioning results in a decrease in norepinephrine release from the locus ceruleus. Trazodone is a prescription medication for humans. Possible side effects include sedation, lethargy, gastrointestinal symptoms (vomiting and/or diarrhea), ataxia, priapism (prolonged erections), increased anxiety, and aggression. Our pet care experts can't wait to welcome you. If they are not available, follow their directions in contacting an emergency facility. However, these symptoms are uncommon. Vomiting Through its activation of the hypothalamic-pituitary-adrenal axis, norepinephrine is associated with fear-based response… Make sure to follow the dosage schedule as recommended.Do not skip doses. If the patient information leaflet in the box is intended for humans, ask your vet for more information about administering this medication to a dog. Clonidine is classified primarily as an alpha-2 agonist. Patients with heart, kidney, or liver disease or closed angle glaucoma should use this medication with caution. Possible side effects of Trazodone In a recent study, Trazodone was found to be well-tolerated with minimal side effects in dogs. It manages depressive moods by controlling how the body releases and absorbs A veterinarian may prescribe the medication for related mental health problems as well. It’s recommended to ask your vet about other side effects that may occur.Side effects from Trazodone typically disappear in a day or two. It’s important that trazodone is stored safely away from pets and that dosage instructions are followed exactly. If a pet takes too … Never give your pet two doses at once or give extra doses.Trazodone is a short-acting drug. If experienced, these tend to have a Severe expression 1. This may cause a serious reaction.Read the labeling on the package before you administer the drug. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. This medication should be used with caution in pets with severe heart disease or liver or kidney impairment. This is especially true if the unwanted behavior is dangerous or aggressive. See below for a comprehensive list of adverse effects. It may be given with food or on an empty stomach. Possible side effects include dilated pupils, sedation, lethargy, vomiting or gagging, colitis (inflammation of the colon), ataxia (loss of muscle control), priapism (persistent and painful erection of the penis), arrhythmias, increased anxiety, increased appetite, and aggression.When trazodone is used with other serotonergic drugs, This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.Trazodone is not recommended in pets hypersensitive to it or those using MAO inhibitors. Your veterinarian may monitor your pet to be sure that the medication is working.Store this medication between 20°C – 25°C (86°F – 77°F). Dry Mouth 5. Dizziness 3. Medications Its use in cats and dogs to treat behavioral disorders is Trazodone is given orally (by mouth) in the form of a tablet. Side effects in dogs are not well documented but are generally mild if present. Alpha-2 agonists increase alpha-2 adrenoreceptor activity. Nausea 8. Animal studies have shown an adverse effect on the developing fetus at very high doses, so the risks of using this medication in pregnant pets versus the benefits will be considered carefully by your veterinarian.The following drugs should be used with caution when given with trazodone: antihypertensive drugs, aspirin, azole antifungals, cisapride, CNS depressants, digoxin, diuretics, fluoroquinolones, macrolide antibiotics, monoamine oxidase inhibitors, metoclopramide, NSAIDs, ondansetron, phenothiazines, SSRI antidepressants, and tramadol.Be sure to tell your veterinarian about any medications (There is no specific monitoring that needs to be done while your pet is taking this medication.