Our website services, content, and products are for informational purposes only. A class of drugs is a group of medications that work in a similar way. Talk to your doctor about other drug options that may work for you.© 2005-2020 Healthline Media a Red Ventures Company. These drugs are often used to treat similar conditions. These issues include:You may need to have blood tests during your treatment with this drug. Some people, according to the advisory, have become depressed or have had their depression worsen, have had thoughts about suicide or dying, or have attempted suicide.In a large-scale study of programs where bupropion was used for smoking cessation or treatment of depression, no withdrawal symptoms were observed.Bupropion is considered moderately dangerous in overdose.In the majority of childhood exploratory ingestions involving one or two tablets, children show no apparent symptoms.Caution should be observed when combining bupropion with a Bupropion inhibits the reuptake of dopamine through the human Bupropion causes antidepressant activity as it selectively inhibits dopamine and norepinephrine re-uptake.The metabolism of bupropion is highly variable: the effective doses of bupropion received by persons who ingest the same amount of the drug may differ by as much as 5.5 times (with a There have been reported cases of false-positive urine amphetamine tests in persons taking bupropion.In 2016, three new major metabolites of bupropion, all formed exclusively by It is synthesized in two chemical steps starting from 3'-chloro-Bupropion was invented by Nariman Mehta of Burroughs Wellcome (now In France, marketing authorization was granted for Zyban on 3 August 2001, with a maximum daily dose of 300 mg;On 11 October 2007, two providers of consumer information on nutritional products and supplements, In April 2008, the FDA approved a formulation of bupropion as a hydrobromide salt instead of a hydrochloride salt, to be sold under the name Aplenzin by In 2012, the U.S. Justice Department announced that GlaxoSmithKline had agreed to plead guilty and pay a $3-billion fine, in part for promoting the unapproved use of Wellbutrin for weight loss and sexual dysfunction.According to the US government classification of psychiatric medications, bupropion is "non-abusable".It is sold under many trade names worldwide and in combinations with It is sold under many trade names worldwide including Aplenzin, Budeprion SR, Bup, Bupredol, Buproban, Bupropion GSK, BuPROPion HCL SR Watson, Bupropion Hydrochloride Anchen, Bupropion Hydrochloride Apotex, BuPROPion Hydrochloride Cadista, Bupropion Hydrochloride Mylan, Bupropion Hydrochloride Sandoz, buPROPion Hydrochloride SR actavis, Bupropion Hydrochloride Sun Pharma, buPROPion Hydrochloride Torrent Pharma, Bupropion Hydrochloride Wockhardt, buPROPion Hydrochloride XL actavis, BuPROPion Hydrochloride XL Watson, Bupropion SR Sanis Health, Bupropionhydrochlorid HEXAL, Bupropionhydrochloride GSK, Buprotrin, Butrin, Buxon, Carmubine, Depnox-SR, Elontril, Elontril XL, Forfivo XL, Funnix, Global buPROPion HCL, Le Fu Ting, Odranal, PMS-Bupropion SR, Prewell, Quomem, ratio-Bupropion SR, Sandoz Bupropion SR, Voxra, Wellbutrin, Wellbutrin Retard, Wellbutrin SR, Wellbutrin XL, Wellbutrin XR, Yue Ting, Zetron, Zyban, Zyban LP, Zybex SR, ZyGenerics Bupropion Hydrochloride XL, and Zyntabac.Substituted amphetamine medication mainly for depression and smoking cessationInChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3This diagram shows the synthesis of bupropion via 3'-chloro-propiophenone. You should set a target quit date within the first 2 weeks of treatment with this drug. As a result, a higher amount of a drug stays in your body for a longer time. Bupropion is an antidepressant that may also be used to help people quit smoking. Other drugs that have the same active ingredients (e.g. You should not need a new prescription for this medication to be refilled. If your symptoms are severe, call 911 or go to the nearest emergency room right away. It is an effective antidepressant on its own, but it is also used as an add-on medication in cases of incomplete response to first-line SSRI antidepressants. Some may be better suited for you than others. Both forms are taken by mouth. • Bupropion hydrochloride extended-release tablets (XL) are contraindicated in patients with a seizure disorder. This drug should only be used if the potential benefit justifies the potential risk.If you become pregnant while taking this drug, call your doctor right away.All possible dosages and drug forms may not be included here. These chemicals include dopamine and norepinephrine.Bupropion oral tablet doesn’t cause drowsiness, but it can cause other side effects.