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(a)Mucous membrane irritant; Note: accidentally opened or damaged capsules require rigorous precautions to avoid inhalation or contact with the skin or mucous membranes (i)Note: swallow whole; local anesthesia of the oral mucosa; choking could occurSlow-release; Note: contains beads that dissolve throughout the GI tractNote: women who are, or may become, pregnant, should not handle crushed or broken tabletsNote: unique drug matrix enhances rapid drug absorptionNote: see package insert for instructions on crushing administrationSlow-release; Note: film coating is designed to break down at or above pH of 7.0Slow-release; Wax-coated; prevents upper GI releaseNote: crushing significantly increases the AUC and TmaxSlow-release (Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal dose)Slow-release; Note: crushing, chewing, or dissolving capsules can cause rapid release and absorption of a potentially fatal doseNote: irritant; avoid contact with skin or mucous membranes; avoid contact with crushed or broken tabletsNote: crushed powder may cause mucous membrane irritation©2020 Institute for Safe Medication Practices. Wall Chart - Oral Dosage Forms that Should Not be CrushedAlso known as the Look-alike and sound-alike (LASA) list. Follow all directions on your prescription label. Page 1 of 16 Oral Dosage Forms That Should Not Be Crushed John F. Mitchell, PharmD, FASHP1 Last updated: January 2014 Drug Product Active Ingredient(s)2 Dosage Form(s) Reasons/Comments3 AcipHex RABEprazole Tablet Extended‐release Actiq fentaNYL Lozenge Slow‐release Note: this lollipop delivery system requires the
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Do not take 2 doses at the same time or extra doses. Your Name: (optional)
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Medications requiring special safeguards to reduce the risk of errors and minimize harm. Author Information .
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Can crush; mix powder with 5-10mL This article has been saved into your User Account, in the Favorites area, under the new folder
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The reports described in Medication Errors were received through the USP-ISMP Medication Errors Reporting Program. President of the Institute for Safe Medication Practices
Tablet Do not divide, crush, chew or disperse3,4 1,4 Alternate bisphosphonate available as injection3 ALLOPURINOL Allopurinol-Apotex Tablet Scored, may be halved3 DB-Allopurinol Tablet Scored, may be halved3 ALUMINIUM HYDROXIDE Alu-Tab Tablet Film coated.