All rights reserved. BMJ 302 (1991): 76226. Use of unopposed estrogens increases the risk of endometrial cancer, while addition of a progestin decreases the risk of Along with its needed effects, estradiol (the active ingredient contained in Estradiol Patch) may cause some unwanted effects. The estrogen patch consists of 17-B Estradiol, a bioidentical estrogen, which is the predominant form of estrogen that our bodies produce when the ovaries are working. Many women report that changing estrogen levels affect their weight, particularly around menopause. Remove the skin patch and call your doctor at once if you have: heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; increased blood pressure- … 4. (No pun intended.) All drugs may cause side effects. They may notice that they are gaining weight, or that it is more difficult to lose weight.So, what is the relationship between a woman’s estrogen levels and her weight?Read on for more information about this phenomenon and what to do about estrogen-related weight gain.Estrogen levels can be low in women for many reasons.One reason why people might gain weight around menopause is changing hormone levels.One form of estrogen called estradiol decreases at menopause. N Engl J Med 300 (1979): 9-1332. Am J Epidemiol 114 (1981): 497-50638. Am J Cardiol 90 (2002): 82-513. Estradiol Cream Side Effects by Likelihood and Severity COMMON side effects . O 05. Gapstur SM, Morrow M, Sellers TA "Hormone replacement therapy and risk of breast cancer with a favorable histology: results of the Iowa women's health study." Nash HA, AlvarezSanchez F, Mishell DR, Fraser IS, Maruo T, Harmon TM "Estradiol-delivering vaginal rings for hormone replacement therapy." This is not a complete list of side effects and others may occur. Obstet Gynecol 70 (1987): 382-33. "Product Information. Oppenheim G "A case of rapid mood cycling with estrogen: implications for therapy." I too will stop this medication. MNT is the registered trade mark of Healthline Media. Gordon J, Reagan JW, Finkle WD, Ziel HK "Estrogen and endometrial carcinoma. Ann Intern Med 74 (1971): 13-2121. These side effects may go away during treatment as your body adjusts to the medicine. Other potential causes of estrogen imbalance include:PCOS is a condition where a woman has multiple small Women with this condition tend to have an issue with weight gain, Estrogen levels remain low after a woman has given birth and while she is breast-feeding. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. These side effects may go away during treatment as your body adjusts to the medicine. Warner Chilcott Laboratories, Rockaway, NJ. Weight Gain If experienced, these tend to have a Less Severe expression 1. Estradiol and progesterone side effects. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Lower levels of estradiol may lead to weight gain. You may report side effects to the FDA at 1-800-FDA-1088.Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. Swelling Of The Abdomen 6. N Engl J Med 325 (1991): 756-6216. 7. Obstet Gynecol 49 (1977): 385-936. Kaufman DW, Palmer JR, de Mouzon J, Rosenberg L, Stolley PD, Warshauer ME, Zauber AG, Shapiro S "Estrogen replacement therapy and the risk of breast cancer: results from the case-control surveillance study." Spengler RF, Clarke EA, Woolever CA, Newman AM, Osborn RW "Exogenous estrogens and endometrial cancer: a case-control study and assessment of potential biases." Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Am J Epidemiol 134 (1991): 1386-9527. If experienced, these tend to have a Severe expression. In effect, this causes menopause. Constipation. Berlex, Richmond, CA. I have been using the Sandoz estradiol Transdermal 0.05 mg/day patch for 3 years approximately. Palmer JR, Rosenberg L, Clarke EA, Miller DR, Shapiro S "Breast cancer risk after estrogen replacement therapy: results from the Toronto Breast Cancer Study." This hormonal change helps to encourage milk production and prevent A woman who has had both of her ovaries surgically removed will go through sudden menopause. Teva Pharmaceuticals USA, North Wales, PA. 2. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Get emergency help immediately if any of the following symptoms of overdose occur:Some side effects may occur that usually do not need medical attention. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Although not all of these side effects may occur, if they do occur they may need medical attention.Some side effects of estradiol may occur that usually Check with your health care professional if any of the following side effects 1. Loss Of Appetite 3. Julian TM "Pseudoincontinence secondary to unopposed estrogen replacement in the surgically castrate premenopausal female." Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.