Protopic is applied to the affected areas twice a day. The most common side effects of Protopic occur where the ointment is applied. In 2006, when the FDA instilled black box warnings on two topical calcineurin inhibitors, Protopic ointment (tacrolimus, Astellas Pharma) and Elidel cream (pimecrolimus, Novartis), it … Protopic is an ointment for treating eczema but it’s not a steroid, instead it is an immunosuppressant containing Tacrolimus, so it doesn’t have the negative side effects that even weak steroids have like thinning of the skin and steroid withdrawal reactions. Do NOT take orally. If you have moderate to severe eczema and you don’t have a medical condition that might make it dangerous to take Protopic, it might be a good option. Keep a list of them with you to show your doctor and pharmacist each time you get a new medicine.Talk to your doctor if you have a skin infection or if side effects (for example, swollen glands) continue or bother you.Call your doctor for medical advice about side effects. Your dosing pattern may differ. Before prescribing Protopic, your health care professional will perform a medical exam and talk to you about your medical history. However, this is a somewhat controversial area. Protopic is usually prescribed after you’ve already been prescribed topical steroid creams but find they haven’t adequately controlled your symptoms. Often, clinicians prescribe Protopic to be applied twice daily for a few weeks, but ask if this is the case for you. Ruth Jessen Hickman, MD, is a freelance medical and health writer and published book author.Casey Gallagher, MD, is board-certified in dermatology and works as a practicing dermatologist and clinical professor. In the U.S., topical Protopic is FDA-approved for the short-term treatment of people with moderate to severe atopic dermatitis (commonly known as “eczema”). Check your prescription to make sure that you are taking the right dose for you.) People with a known allergy to Protopic should not use it. Call your doctor right away if the product is swallowed. The lower dose is FDA approved for individuals 2 years and older, and the more concentrated version is only approved for people age 16 and older. It’s important not to confuse topical creams like Protopic with drugs taken orally. Avoid getting Protopic into your eyes or mouth or on unaffected areas of skin. Eucrisa (crisaborole) is a drug that works in a different way than these other options. These mild to moderate issues happen most frequently within the first few days of treatment. Some of these include: Because of the way it is absorbed, Protopic is unlikely to cause interactions with drugs that you take by mouth. If you have signs of an allergic reaction (hives, difficulty breathing, swelling of the lips), you’ll need to seek emergency medical attention right away. 2-15 years: 0.03% ointment: Apply thin layer to affected area q12hr >15 years: Apply 0.03% or 0.1% ointment as thin layer to affected area q12hr; discontinue treatment when symptoms have cleared; if no improvement within 6 … Read the Medication Guide every time you or a family member gets ProtopicTell your doctor about all the medicines you take and skin products you use including prescription and nonprescription medicines, vitamins, and herbal supplements.Know the medicines you take. Normally this valuable organizing is suggested regarding using a second time everyday. It appears to be an effective, low-risk treatment that is approved for people with mild to moderate eczema. Ask your health care provider in regards to the volume to use daily schedule anytime commencing to have Protopic Ointment. These data demonstrate that after a single application of ointment to intact and abraded skin, the concentration of tacrolimus in lymph (mesenteric node) was greater than in blood.