This is not a complete list of side effects and others may occur. "Leflunomide use during the first 33 months after food and drug administration approval: Experience with a national cohort of 3,325 patients." O 0Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Tell your doctor if you have serious side effects of Arava including: Ann Pharmacother 36 (2002): 1009-1111. Diarrhea or constipation. Commonly reported side effects of exenatide include: diarrhea, nausea, and vomiting. J Rheumatol 34 (2007): 2201-33. It is unknown whether exenatide extended-release causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of exenatide extended-release-induced rodent thyroid C-cell tumors has not been determined.Exenatide extended-release is contraindicated in patients with a personal or family history of MTC and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). 2. 1. Arthritis Rheum 56 (2007): 2094-20967. Call your doctor for medical advice about side effects. Amylin Pharmaceuticals Inc, San Diego, CA. Call your doctor for medical advice about side effects. Ann Pharmacother 37 (2003): 149Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. This is not a complete list of side effects and others may occur. Clin Pharmacol Ther 75 (2004): 580-512. O 04. In rare cases, Arava may cause serious or fatal liver disease. J Rheumatol 32 (2005): 1160-38. Byetta (exenatide)." You may report side effects to FDA at 1-800-FDA-1088. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Upset stomach or throwing up. "Product Information. Astra-Zeneca Pharmaceuticals, Wilmington, DE. O 05. Subcutaneous route (Powder for Suspension, Extended Release; Suspension, Extended Release)Exenatide extended-release causes an increased incidence in thyroid C-cell tumors at clinically relevant exposures in rats compared to controls. Common side effects of Arava include: diarrhea, nausea, stomach pain, loss of appetite, weight loss, headache, dizziness, back pain, numbness or tingling, runny or stuffy nose, cold symptoms, or ; itching or skin rash. The table below contains some of the most common ones associated with leflunomide. Severe liver injury, including fatal liver failure, has been reported in patients treated with leflunomide. 6. Kaltwasser JP, Nash P, Gladman D, et al. "Risk of interstitial lung disease associated with leflunomide treatment in Korean patients with rheumatoid arthritis." Arthritis Rheum 50 (2004): 1939-502. Other side effects include: bronchitis, hypersensitivity condition, hypertension, pruritus, rhinitis, and tenosynovitis. "Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis: a multinational, double-blind, randomized, placebo-controlled clinical trial." Common side effects of Arava include: alopecia, diarrhea, increased serum alanine aminotransferase, increased serum aspartate aminotransferase, and skin rash. Cerner Multum, Inc. "UK Summary of Product Characteristics." J Rheumatol 29 (2002): 1806-710. 3. Do not use in patients with acute or chronic Along with its needed effects, leflunomide (the active ingredient contained in Some side effects of leflunomide may occur that usually Check with your health care professional if any of the following side effects A 54-year-old female with rheumatoid arthritis experienced acute A 46-year-old woman with erosive and refractory rheumatoid arthritis (RA) developed sudden focal hair loss (A 61-year-old female with severe rheumatoid arthritis experienced A 69-year-old male with a 19-year history of rheumatoid arthritis experienced hypersensitivity pneumonitis coincident with leflunomide (the active ingredient contained in Arava) therapy. Arava (leflunomide)." The temporal association and resolution following discontinuation suggest leflunomide was the causative agent.The risk of pancytopenia appears to be increased when leflunomide is combined with A 69-year-old male with stable rheumatoid arthritis experienced liver 1. "Product Information. "Product Information. Arthritis Rheum 49 (2003): 745-519. Cerner Multum, Inc. "Australian Product Information." You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Hyeon Ju J, Kim SI, Lee JH, et al. Common side effects may include: heartburn, nausea, vomiting, diarrhea, constipation; headache, dizziness; weakness; or; feeling jittery. Hill RL, Topliss DJ, Purcell PM "Pancytopenia associated with leflunomide and methotrexate." McCoy CM "Leflunomide-associated skin ulceration." Int J Dermatol 45 (2006): 1370-113. Three months after being administered leflunomide 20 mg once a day, he presented with a 1-month history of progressive dyspnea, decreased appetite, and weight loss. Takeishi M, Akiyama Y, Akiba H, Adachi D, Hirano M, Mimura T "Leflunomide induced acute interstitial pneumonia."