Ask your doctor about any risk.Acyclovir should not be given to a child younger than 2 years old.Take acyclovir exactly as prescribed by your doctor. This inhibition is accomplished in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase.Systemic exposure following topical administration of acyclovir is minimal. Another study, enrolling 251 healthy adults, was conducted to evaluate the contact sensitization potential of Acyclovir Cream using repeat insult patch testing methodology. Safety and effectiveness in pediatric patients less than 12 years of age have not been established.Clinical studies of Acyclovir Cream did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Patients should be instructed to wash hands prior to application and ensure the face and/or lips are clean and dry. Available for Android and iOS devices. Skipping doses may increase the risk of your virus becoming resistant to medication.Lesions caused by herpes viruses should be kept as clean and dry as possible. Avoid touching an infected area and then touching your eyes. Acyclovir cream was evaluated in two double-blind, randomized, placebo (vehicle)- controlled trials for the treatment of recurrent herpes labialis. Patients should be instructed that Acyclovir Cream is intended for cutaneous use only for herpes labialis of the lips and around the mouth. 14 CLINICAL STUDIES . Your symptoms may get better before the infection is completely treated. Information on these studies is available in the full prescribing information for Acyclovir Capsules, Tablets, and Suspension and Acyclovir for Injection. In both studies, the mean duration of the recurrent herpes labialis episode was approximately one-half day shorter in the subjects treated with Acyclovir Cream (n = 682) compared with subjects treated with placebo (n = 703) for approximately 4.5 days versus 5 days, respectively. In this trial, therapy was applied using the same dosing regimen as in adults and subjects were followed for adverse events. Hypersensitivity to baclofen. Considering prescribing an episodic oral antiviral such as aciclovir or valaciclovir, for healthy people with a primary or recurrent infection if lesions are frequent, persistent, or severe; people with recurrent gingivostomatitis; and people who are immunocompromised with primary or recurrent infection, depending on clinical judgement. The average patient had five episodes of herpes labialis in the previous 12 months. Lioresal ® Intrathecal is not recommended for intravenous, intramuscular, subcutaneous or epidural administration. No significant difference was observed between subjects receiving Acyclovir Cream or placebo in the prevention of progression of cold sore lesions.An open-label, uncontrolled trial with Acyclovir Cream was conducted in 113 patients aged 12 to 17 years with recurrent herpes labialis. Of 202 evaluable subjects, possible cutaneous sensitization reactions were observed in the same 4 (2%) subjects with both Acyclovir Cream and placebo, and these reactions to both Acyclovir Cream and placebo were confirmed in 3 subjects upon rechallenge. Acyclovir Cream is intended for cutaneous use only and should not be used in the eye or inside the mouth or nose.Acyclovir Cream has a potential for irritation and contact sensitization [see The effect of Acyclovir Cream has not been established in immunocompromised patients.Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug, and may not reflect the rates observed in practice.In five double-blind, placebo-controlled trials, 1124 patients were treated with Acyclovir Cream and 1161 with placebo (vehicle) cream. Patients should be advised that Acyclovir Cream should not be used in the eye, inside the mouth or nose, or on the genitals. Due to minimal systemic absorption of Acyclovir Cream, systemic drug interactions are unlikely.There are no adequate and well-controlled studies of Acyclovir Cream in pregnant women. Patients should be instructed to avoid applying other topical products to the affected area while using Acyclovir Cream.Do not use if you are allergic to Acyclovir Cream or any of the ingredients in Acyclovir Cream. Acyclovir Cream is a herpes simplex virus (HSV) nucleoside analogue DNA polymerase inhibitor indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents 12 years of age and older.Acyclovir Cream should be applied 5 times per day for 4 days. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Sitavig will not treat genital herpes.Take acyclovir for the entire length of time prescribed by your doctor. Information on these studies following systemic exposure is available in the full prescribing information for acyclovir products approved for oral and parenteral administration. 14 CLINICAL STUDIES. Patients should be advised to apply Acyclovir Cream topically 5 times per day for 4 days.