It's one of the more interesting TCAs, certainly. Food for thought. The initial side-effects of the Mirtazapine were worth the decrease in anxiety and depression for me. The site may not work properly if you don't If you do not update your browser, we suggest you visit Press J to jump to the feed. I’ve hit snooze every 10 minuets for 3 hours straight. ..Kinda ranted there. One thing which I have experienced is a nasty taste in mouth all the time. Elevated cholesterol levels After reading that this could be a potential side effect, I made sure to get my cholesterol levels checked before I … It just stopped work Overall, I would definitely recommend this drug opposed to an SSRI like Prozac or Lexapro, BUT with that being said, every person works differently with different drugs. I guess he can see the state I’m in at this dose so figures the pros of quick drop outweigh the cons? So I gave remeron a shot this helped with eating (I gained all the weight back and more) but this didn’t really help with sleeping because I have major insomnia. This pill is better than sertraline for me and worked quicker, within days for the worst anxiety. There wasn’t a point that I knew that I was satiated. Pharmacological inference and discussion is well and good, but bio-assay is king.I do plan on trying it, actually. breast pain or tenderness; This drug is disaster waiting to happen for me. Please keep trying.” I wouldn't go as far as saying it cured me though. I have picked up 2kgs but am training 4 times per week to compensate. I have been on every conceivable anti-depressant and none have been as effective as mirtazapine for my anxiety (and resulting depression)” I didn’t feel that it was helping me at all. Anyways that's my 2 cents worth. Would I have like to do it more quickly? I mean really - check this out:The 5-HT2C receptor is known to inhibit the release of the neurotransmitters dopamine and norepinephrine in various parts of the brains of rodents, notably in reward pathways such as the ventral tegmental area. What kinds of side effects have you experienced (especially somnolence)?At higher doses, the H1 histamine antagonism is going to be overrided by its potent NErgic effects. In fact, if you look through the scientific literature, there are very few recorded case reports of withdrawals [7-9]. “This mirtazapine saved my job, my life and my relationship. How long do the side effects last for.” Medication binned after 1 tablet I would take anxiety over these any day” 5-HT2C inverse agonists have been shown to inhibit mesoaccumbens dopamine outflow[86] attenuating the rewarding properties of various substances like morphine.Buuuut it's also an antagonist or inverse agonist at 5-HT2A, whose activation decreases dopamine release, similar to 5-HT2C (I actually think the indirect activation of these puppies by SSRIs is what causes the emotional flatlining / apathy / worsening ADHD-like symptoms), which I like. I really think SSRI's are pushed more often than bc of big pharmaceutical company kick backs and marketing. Content includes images, text, audio, video, and any other forms of content appearing on The Panicked Foodie. I'm already struggling with shedding some weight off; taking this medication on the regular would've just made me even more depressed due to the inevitable weight gain. Congrats on getting off so quickly. My Dr. put me on melatonin 3mg + Mirt 7.5 to swap out for Xanax .5mg nightly to turn off my brain so I could sleep. Some scary reviews on here but in my experience , positives outweigh the bad. Because who doesn’t like sweets?!? These startup side effects only lasted about a week or so. If you are US based, you have to ask your doctor to send a script to a compounding pharmacy and they will make a suspension for you. I really think SSRI's are pushed more often than bc of big pharmaceutical company kick backs and marketing. But a reminder from past experience I am seeing a counsellor who is teaching me lots of techniques to deal with my anxiety. Excellent for sleep as I was struggling massively before starting this, although I do tend to feel bit tired during the day particularly at weekends.