Talk to your doctor about other drug options that may work for you.© 2005-2020 Healthline Media a Red Ventures Company. No data are available for use of memantine in patients with renal failure on dialysis. This can lead to more side effects. Memantine and donepezil combination is used to treat dementia (memory loss and mental changes) associated with moderate or severe Alzheimer's disease. Instead, the best way to dispose of your medication is through a medicine take-back program. This guidance should not be understood as being legally enforc eable and is without prejudice to the need to ensure that the data submitted in support of . For memantine, the following should be considered:Tell your doctor if you have ever had any unusual or allergic reaction to memantine or any other medicines. Serious side effects and their symptoms can include the following:Memantine oral tablet can interact with several other medications. Memantine hydrochloride 10 mg film-coated tablets contain 10 mg memantine hydrochloride equivalent to 8.31 mg memantine. The physician should initiate dosage at a low level and increase it gradually, noting carefully the clinical … Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Other side effects not listed may also occur in some patients. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Follow your doctor's orders or the directions on the label. In these cases, your doctor may want to change the dose, or other precautions may be necessary. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse.Memantine is available only with your doctor's prescription.In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This means it is still under development and may contain inaccuracies. Do not stop taking memantine without talking to your doctor.Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient.This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.Unless your doctor tells you otherwise, continue your normal diet.Take the missed dose as soon as you remember it. Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane.A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. Memantine is predominantly eliminated by the kidneys in part by tubular secretion. Healthline Media does not provide medical advice, diagnosis, or treatment. This is thought to cause damage to the brain cells in people with Alzheimer’s disease.Memantine works by blocking the receptors in the brain that glutamate would normally bind to. The following list contains some of the key side effects that may occur while taking memantine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of memantine, take it as soon as possible. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Important Notice: The Drugs.com international database is in BETA release. 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