Most pregnant women who develop gestational diabetes insipidus have a mild case that does not cause noticeable symptoms. A more effective treatment tends to be a combination of diuretics and NSAID medications. This form of DI is the only version that can actually be … The same events and conditions that damage the hypothalamus or pituitary—surgery, infection, inflammation, a tumor, head injury—can also damage the thirst mechanism. Here is an in-depth look at this disease and what a diagnosis may mean.Central diabetes insipidus is the most common form of DI because it occurs in all population demographics. There are genetic versions of this disease and it can be caused by an injury as well. It will create more when too many fluids are present.In 3 out of the 4 types of diabetes insipidus, the regulation system malfunctions and causes the kidneys to think that there is too much water in the body. An MRI may include an injection of a special dye, called contrast medium. In return, people with central diabetes insipidus feel consistently thirsty because their kidneys are taking out too much water.Treatment options for this form of DI are good. The nearby pituitary gland stores the vasopressin and releases it into the bloodstream when the body has a low fluid level. The symptoms of DI may also be present from birth or may develop slowly over time throughout childhood.An overabundance of certain minerals may also cause this form of DI. People who chronically take lithium, for example, have a 40% chance of developing this form of DI. This creates urine concentration. The disruption of vasopressin causes the kidneys to remove too much fluid from the body, leading to an increase in urination. For some reason, taking ibuprofen and other OTC painkillers concentrates the urine within the kidneys and relieves many of the bothersome symptoms of DI.Most treatment options are effective for nephrogenic diabetes insipidus, but because of the individualized nature of this disease, finding the right combination can take some time. Treatment for frequent urination or constant thirst depends on the patient’s type of diabetes insipidus:Most people with diabetes insipidus can prevent serious problems and live a normal life if they follow the health care provider’s recommendations and keep their symptoms under control.Researchers have not found that eating, diet, and nutrition play a role in causing or preventing diabetes insipidus.The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and other components of the National Institutes of Health (NIH) conduct and support research into many diseases and conditions.Clinical trials are part of clinical research and at the heart of all medical advances. Signs of dehydration includeSevere dehydration can lead to seizures, permanent brain damage, and even death.Usually, people can prevent dehydration by increasing the amount of liquids they drink. The urine flows from the kidneys to the bladder through tubes called ureters. Not only does the hypothalamus control ADH levels through the pituitary gland, but it is also responsible for the thirst mechanisms that people experience. Others can control their DI symptoms through hormone replacements or other medications. Types of Diabetes Insipidus. This will just create more stress and anxiety, which can enhance the symptoms. When diabetes insipidus is the diagnosis, then the body cannot properly control the balance of fluids within it. The test can show whether the urine is dilute or concentrated. The kidneys do more than just filter the blood to eliminate impurities. Up to 30% of the cases of diabetes insipidus that are eventually diagnosed do not have a contributing medical cause to it that has been discovered. Depending on how many fluids are consumed over the course of the day, a person with diabetes insipidus may expel over 20 liters of urine over the course of 24 hours.Normally the human body creates an anti-diuretic hormone (ADH) called Vasopressin that is stored in the pituitary gland. A lucky few will have their symptoms resolve.Use the information here to ask questions about diabetes insipidus if you see the signs and symptoms of it at your next medical appointment. Many women simply increase their water intake to prevent dehydration and are monitored by their doctors to prevent disease development.The other 3 versions of DI cause people to not have enough water. These extra fluids become urine and this gets stored in the bladder. Do not self-diagnose. When the body is unable to regulate how it handles the fluids that are within it, then diabetes insipidus will occur. The end result is that people with diabetes insipidus will … For updates or for questions about any medications, contact the U.S. Food and Drug Administration toll-free at 1-888-INFO-FDA (1-888-463-6332) or visit
This content is provided as a service of the The National Institute of Diabetes and Digestive and Kidney Diseases Diabetes mellitus causes high blood glucose, or blood sugar, resulting from the body's inability to use blood glucose for energy. When the body gets dehydrated, more ADH is produced to tell the kidneys to absorb more water. The enzymes interfere with the communication systems between the kidneys and the hormone and will even counteract the hormone to reduce the amount there is within the body.The good news for expectant mothers is this: virtually all cases of gestational DI will resolve themselves in 6 weeks or less after the pregnancy.