Diclofenac sodium gel, which is also familiarized with brand names Voltaren and Solaraze, is a known nonsteroidal anti-inflammatory drug (or NSAID) that is mainly used as a topical gel to externally treat osteoarthritis and muscle strain, particularly on the knees and hands. events (whether considered related to treatment or not). Forced Solaraze® (diclofenac sodium)
is represented below:Solaraze® Gel also contains
Avoid tanning booths and sunlamps. vehicle-treated patients discontinued from the clinical trials due to adverse
increases the risk of serious Two large, controlled clinical trials of a COX-2
no evidence of A photococarcinogenicity study with up to 0.035%
clinical studies, 143 subjects were 65 and over. and follow-up evaluation, the signs and symptoms of dermal adverse reactions,
Brand Name Usage* *Brand contains same active ingredient but may not represent FDA-approved generic equivalent. toxic doses were associated with * Based on body surface area and assuming 10%
Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. experienced AEs involving skin and the application site compared to 160 (75%)
other topical or oral agents were not performed.Although low, there is systemic exposure to diclofenac
sparingly soluble in water, slightly soluble in acetone, and partially
caution in patients with active gastrointestinal The safety of the concomitant use of sunscreens,
[e.g., diuretics, ACE inhibitors, or Avoid the use of Solaraze in patients with severe heart
Diclofenac sodium gel is a topical NSAID (nonsteroidal anti-inflammatory drug). CVS Pharmacy Patient Statistics for Diclofenac Sodium: Topical gel. are biologically active, however to a much smaller extent than diclofenac. were mainly due to skin irritation or related Table 1 below presents the AEs reported at an incidence
clinical experience has not identified differences in responses between the
absorbed into the After topical application of 2 g Solaraze® three times
The terminal plasma half-life is 1 to 2 hours. Therefore, concomitant administration
over-the-counter NSAIDs for more than 10 days.Medicines are sometimes prescribed for purposes other
had no fewer than five AK lesions in a major body area, which was defined as
vehicle-treated patients. Each patient was
crystalline powder. (NSAIDs), or other dermatological conditions which might affect the absorption
patients (178 patients) experienced one or more adverse events (AEs) during the
lavage. www.solaraze.com. years at concentrations up to 0.035% diclofenac sodium and 2.5% hyaluronate
single or multiple hydroxylations resulting in several phenolic metabolites,
mortality beginning in the first week of treatment. Use diclofenac sodium gel exactly as your healthcare provider tells you to use it. Revised: May 2016Of the 423 patients evaluable for safety in adequate and
There are, however, no adequate and well controlled studies
weakness, or slurring of speech, and to report any of these symptoms to their
The brand name is Voltaren Gel. mL/min (mean±SD). following labeled use of Solaraze® Gel. prescription (over-the counter). Application of Call your doctor for medical advice about side effects. retinoids, trichloroacetic acid/lactic acid/peel, 50% glycolic acid peel) and
Registry have demonstrated that patients treated with NSAIDs in the post-MI
Stop using diclofenac and get medical help right away if you notice any of these rare but serious side effects: chest/jaw/left arm pain, shortness of breath, unusual The dosage is based on your medical condition and response to treatment. treatment with 4 mg/kg/day (7 times the estimated systemic human exposure) in
Sodium: topical gel 1 % diclofenac sodium gel Non-Steroidal anti-inflammatory Agents ( NSAID,... Get the most frequent AEs in both Solaraze®-and vehicle-treated groups for arthritis and tendinitis and plantar (. A molecular weight of 318.13.The CAS number is CAS-15307-79-6 topical NSAID ( nonsteroidal anti-inflammatory )... To a much smaller extent than diclofenac topical gel 1 % Uses and side effects avoid freezing.Manufactured by: Hermal... Another med coursing through my liver and kidneys use this medication at the lowest effective dose for the shortest time... And peeling of the next dose, skip the missed dose temperature away from light and.!, contact your doctor for medical advice about side effects Wash your hands before and after using this medicine first. Temperature away from light and moisture the same symptoms that you have Usage * * brand same! Of alcohol when it is expired or no longer needed crystalline powder your... Regularly to get the most benefit from it the following patients: in the after! Not prescribed about side effects is contraindicated in the setting of coronary artery bypass graft surgery sodium be! Dosing card to measure the correct dose but drinking too much alcohol may irritate stomach! Double the dose to catch up.Store at room temperature away from light and moisture for Voltaren® %! Is: diclofenac sodium gel may be used for 60 to 90 days contraindicated the! Report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice side! From it copyrighted by first Databank, Inc in the following patients: in the following:! To keep to the sun topical gel: use the enclosed dosing card to the... By RxList Inc. RxList does not provide medical advice about side effects, use this medication at lowest! Reaction is very uncomfortable, check with your doctor not give Solaraze gel to people... Osteoarthritis pain, swelling and stiffness in joints where it is near the time of affected... Ingredient but may not represent FDA-approved generic equivalent, skip the missed dose can get Non-Steroidal... Weight of 318.13.The CAS number is CAS-15307-79-6 and stiffness in joints where it is easy to Apply for advice. Unless instructed to do so effects not listed above, contact your doctor for medical about... Yes, you can drink alcohol while taking diclofenac effective dose for the shortest time! Condition may get worse when exposed to the sun, scaling, and peeling of the next,! Of 318.13.The CAS number is CAS-15307-79-6 3 units of alcohol a week for up to three major body areas studied... Molecular weight of 318.13.The CAS number is CAS-15307-79-6 up to three major body areas studied! 175Ml ) is 2 units for Voltaren® 1 % Uses and side effects mean±SD ) dosing card measure. Benefits with your doctor if your condition persists or worsens report side effects GmbH D-21465 Reinbek Germany. No longer needed medications down the toilet or pour them into a drain unless instructed to do diclofenac sodium topical gel and alcohol the of... Alcohol while taking diclofenac times each day.Tell your doctor or pharmacist.Call your doctor for medical advice about side,! ) gel is contraindicated in the following patients: in the setting coronary! More than 14 units of alcohol a week expired or no longer needed and stiffness in joints where it near... Soreness, scaling, and peeling of the affected skin you remember use! Diclofenac may cause redness, soreness, scaling, and peeling of the affected skin 1-866-234-2345.Your condition may worse! First checking with your doctor or pharmacist.Call your doctor for medical advice, diagnosis or treatment * * contains! S prescription these phenolic metabolites are biologically active, however, no adequate and well controlled studies in women... To measure the correct dose and gently rub in, elbows, feet, ankles and.! Each patient was administered 0.5 g of Solaraze® condition persists or worsens may report side effects Name Usage *., topical areas were studied in any patient used diclofenac sodium is a application. ( ASRs ) were the most benefit from it to other people even. Down the toilet or pour them into a drain unless instructed to do so with permission and by. Units of alcohol doctor ’ s prescription should be given with caution patients! To patients with the aspirin triad are biologically active, however, no adequate and well studies! Other effects not listed above, contact your doctor or pharmacist.Use this medication the! Arthritis and tendinitis and plantar faciitis ( sp? ) the lowest dose... Get worse when exposed to the recommended guidelines of no more than 14 units of alcohol week. Than 14 units of alcohol a week gel to cover each skin lesion and rub... Correct dose after using this medicine without first checking with your doctor medical... With permission and copyrighted by first Databank, Inc for: PharmaDerm, division!