Visit the MedicineNet does not provide medical advice, diagnosis or treatment. Digoxin increases the strength and efficiency of heart contractions, and is useful in the treatment of heart failure and control the rate and rhythm of the heart. The injection is buffered to a pH of 6.8 to 7.2 with 0.17% sodium phosphate and 0.08% anhydrous citric acid. Care must be taken to avoid toxicity if digoxin is used.Digoxin should be used with caution in patients with acute myocardial infarction. Signs and symptoms of digoxin toxicity become more frequent with levels above 2 ng/mL. Any arrhythmia or alteration in cardiac conduction that develops in a child taking digoxin should be assumed to be caused by digoxin, until further evaluation proves otherwise.The signs and symptoms of toxicity are generally similar to those described in the ADVERSE REACTIONS section but may be more frequent and can be more severe. Nevertheless, caution should be exercised when digoxin is administered to a nursing woman.Newborn infants display considerable variability in their tolerance to digoxin. The syringe should Slow infusion of Lanoxin Injection Pediatric is preferable to bolus administration. Diagnosis and treatment of chest pain depends upon the cause and clinical presentation of the patient's chest pain.An arrhythmia is an abnormal heart rhythm. See prescribing information for dosage information.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. These adverse experiences are consistent with results from a large, placebo-controlled mortality trial (DIG trial) wherein over half the patients were not receiving digoxin prior to enrollment.The side effects of digoxin in infants and children differ from those seen in adults in several respects. Digoxin should not be used for the treatment of multifocal atrial tachycardia.LANOXIN is indicated for the treatment of mild to moderate heart failure. failure; and diastolic or right-sided heart failure. Reduce digoxin concentrations by decreasing the digoxin dose by approximately 15-30% or by modifying the dosing frequency and continue monitoring. Each 1-mL ampul contains 100 mcg (0.1 mg) digoxin. Rarely, the use of digoxin has been associated with abdominal pain, intestinal ischemia, and hemorrhagic necrosis of the intestines.Digoxin can produce visual disturbances (blurred or yellow vision), headache, weakness, dizziness, apathy, confusion, and mental disturbances (such as anxiety, depression, delirium, and hallucination).Gynecomastia has been occasionally observed following the prolonged use of digoxin. This leads to better blood circulation and reduced swelling of the hands and ankles in patients with heart problems. About two-thirds of adult patients with clinical toxicity have serum digoxin concentrations greater than 2.0 ng/mL. Overview of Drugs. The end metabolites, which include 3 β-digoxigenin, 3-keto-digoxigenin, and their glucuronide and sulfate conjugates, are polar in nature and are postulated to be formed via hydrolysis, oxidation, and conjugation. stage of the disease.Heart rhythm disorders vary from minor palpitations, premature atrial contractions (PACs), premature ventricular contractions (PVCs), sinus tachycardia, and sinus brachycardia, to abnormal heart rhythms such as tachycardia, ventricular fibrillation, ventricular flutter, atrial fibrillation, atrial flutter, paroxysmal supraventricular tachycardia (PSVT), Wolf-Parkinson-White syndrome, brachycardia, or heart blocks. Diabetes The prognosis if palpitations depends on the underlying cause.Atrial flutter is a problem with the atria of the heart. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. To achieve maximum benefits, do a mix of stretching exercise, aerobic activity, and strengthening exercise. Treatment of palpitations may include lifestyle changes, medication, ablation, or implantation of a pacemaker. Treatment of heart failure consists of lifestyle modification and taking medications to decrease fluid in the body and ease the strain on the heart.