A trend toward a greater incidence of gallbladder surgery was observed for the Gemfibrozil group (17 versus 11 subjects, a 54% excess). You may report side effects to FDA at 1-800-FDA-1088.We comply with the HONcode standard for trustworthy health information - Gemfibrozil pharmacokinetics are affected by the timing of meals relative to time of dosing. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. An adequate study to test for peroxisome proliferation has not been done in humans but changes in peroxisome morphology have been observed. Gemfibrozil is highly bound to plasma proteins and there is potential for displacement interactions with other drugs (see The initial treatment for dyslipidemia is dietary therapy specific for the type of lipoprotein abnormality. The hazard ratio (Gemfibrozil:placebo) for cardiac events was 1.47 (95% confidence limits 0.88 to 2.48, p=0.14). Each Gemfibrozil tablet intended for oral administration contains 600 mg of Gemfibrozil. A clinically and statistically significant reduction in myocardial infarctions was seen in the concurrent nicotinic acid group compared to placebo; no reduction was seen with clofibrate.The mechanism of action of Gemfibrozil has not been definitely established. The concomitant administration of Gemfibrozil with simvastatin is contraindicated (see 6. To avoid this, it may be recommended to separate your statin dose and bile acid sequestrant dose by … You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. In this study of patients with known or suspected coronary heart disease, no benefit from Gemfibrozil treatment was observed in reducing cardiac events or cardiac deaths. Although not all of these side effects may occur, if they do occur they may need medical attention. Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Over the five-year study period, the Gemfibrozil group experienced a 1.4% absolute (34% relative) reduction in the rate of serious coronary events (sudden cardiac deaths plus fatal and nonfatal myocardial infarctions) compared to placebo, p=0.04 (see Table I). Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Do not store in the bathroom. After approximately 6.5 years following randomization, all patients were informed of their original treatment group and lipid values during the five years of the double-blind treatment. If cholelithiasis is suspected, gallbladder studies are indicated. These medications are not usually taken together. Deaths from any cause during the double-blind portion of the study totaled 44 (2.2%) in the Gemfibrozil randomization group and 43 (2.1%) in the placebo group. Of the 35 patients in the Gemfibrozil group who experienced cardiac events, 12 patients suffered events after discontinuation from the study. Properly discard this product when it is expired or no longer needed. These included hypesthesia, paresthesias, and taste perversion. Further information is available from a 3.5 year (8.5 year cumulative) follow-up of all subjects who had participated in the Helsinki Heart Study. nexium and levothyroxine Is lisinopril HCTZ, gemfibrozil, Nexium, or levothyroxine recalled. eHealthMe has been monitoring drugs since 2008. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Carcinogenesis, Mutagenesis, Impairment of FertilityAdditional adverse reactions that have been reported include cholecystitis and cholelithiasis (see To report SUSPECTED ADVERSE REACTIONS, contact Viona Pharmaceuticals Inc. at 1-888-304-5011 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.Call your doctor for medical advice about side effects.