This version is often referred to as Claritin-D.Loratadine was first discovered in 1981, and first became commercially available in 1993. The usual dosage for cats is 5 mg every 24 hours. Always notify your veterinarian of medications (prescribed or non-prescribed) before the skin tests to ensure accurate results.Before giving loratadine, make sure that your cat is not taking other antihistamines or medications like cimetidine, macrolide antibiotics (erythromycin), or ketoconazole, which may interact with loratadine.The length of time your cat is on loratadine depends on the condition treated and how the cat responds to the medication. As the name suggests, the drug combats histamine, a natural chemical in the body. The average dose is 62. Benadryl (diphenhydramine) and Claritin (loratadine) are antihistamines used to treat allergy symptoms, such as itching, hives, runny nose, watery eyes, and sneezing from hay fever (allergic rhinitis) and other allergies, such as allergies to molds and dust mites. Ensure to follow the dosage as recommended by your vet. Combination medications for humans that include a decongestant may be harmful to your cat’s health.If you’re using loratadine to minimize allergic effects of a vaccination, you will likely see the best results if you administer the medication to your cat prior to her receiving the vaccination.If you’re using loratadine to treat itchy feline skin, you may see better results if you combine the antihistamine with fatty acid supplements.As a second-generation antihistamine, loratadine causes fewer side effects than the traditional antihistamines, but there are still a few side effects that cat owners need to know. When a cat has an allergic response, mast cells and basophils release histamine which binds to cells containing H1 receptors.H1 – Located in the smooth muscles, lining of blood vessels and airways.Common allergies in cats include flea allergies, food, dust and Loratadine is available in 5 and 10 mg tablets and syrup. Loratadine is an antihistamine that works selectively on peripheral histamine-1 (H-1) … Common feline allergens include flea saliva, house dust mites and common food ingredients, and typical allergy symptoms can include irritated skin, itching or swelling. Claritin is the brand name for the active drug called Loratadine. Loratadine, a member of the piperidine class of antihistamines, has gotten relatively positive reviews in particular for the treatment of feline itchy skin but actual published studies are few. excessive scratching. BACKGROUND: The oral administration of loratadine, an antihistamine, can have a variety of adverse side effects, such as headache, fatigue, and nausea, because of the transient high blood concentration. It is the histamine that produces the unwelcome symptoms we know as an allergic reaction, including sneezing, watery eyes, runny nose and itchiness. Concurrent Treatment. It is a popular choice because of its non-sedating qualities.As will become clear later, it is important to recognize that there is a second version, which contains Loratadine, but also has the added ingredient pseudoephedrine, which is a decongestant. Liquid Benadryl is most recommended as it is easier to measure out. But what about if your canine companion is suffering from allergies himself. Keep human and pet medication in separate containers to avoid mixing medications and accidental administration of the wrong medication.Julia Wilson is a cat expert with over 20 years of experience writing about a wide range of cat topics, with a special interest in cat health, welfare and preventative care.Julia lives in Sydney with her family, four cats and two dogs. Initially, your cat may need cortisone and antihistamines. Veterinarians weigh in on whether Benadryl is safe for cats.