Most MCDK are unilateral, with the left kidney more often affected (53.1%) . Aslam M, Watson AR; Trent & Anglia MCDK Study Group.Arch Dis Child. In conclusion, we want to emphasize optimal use of ultrasound imaging to detect such abnormalities as early as possible to guide the proper management. extracted independently relevant data regarding study characteristics and pregnancy outcome. Clipboard, Search History, and several other advanced features are temporarily unavailable. In 7.2% of cases, the initial diagnosis was revised, either pre‐ or postnatally; hydronephrosis was the common differential diagnosis. In nine cases, the initial antenatal diagnosis of suspected MCDK was revised, either later in pregnancy (Antenatal ultrasound had a diagnostic accuracy of about 91% in the prediction of postnatal MCDK and can therefore be used to guide antenatal counseling. All patients had the diagnosis confirmed with radioisotope scans and micturating cysto‐grams. Vesicoureteric reflux (VUR), pelviureteric junction obstruction, vesicoureteric junction obstruction, and ureterocele are the most commonly seen abnormalities in contralateral kidney. Given the natural history of MCDK, this was interpreted as confirmation of the antenatal diagnosis rather than misdiagnosed renal agenesis. Although the prognosis was thus largely unaltered, parents should be made aware of this possibility at the time of the diagnosis at the midtrimester anomaly scan. Multicystic renal dysplasia (MCRD) is the most common cause of abnormally enlarged kidney, diagnosed on antenatal ultrasound examination. It is an abnormality of the embryonic development in which the renal parenchyma is substituted by nonfunctioning renal tissue made up of cysts which do not communicate with each other. The incidence of MCDKD is about 1 in 5,000-10,000 births . Objective To document the urological problems associated with multicystic renal dysplasia (MCRD), to assess the efficacy of radiological methods for following the natural history of MCRD and to review current experience in the light of historical data regarding this condition. In this paper, we describe a prenatal presentation of multicystic dysplastic kidneys and anhydramnios in a male fetus with a postnatal autopsy finding of … In this paper, we describe a prenatal presentation of multicystic dysplastic kidneys and anhydramnios in a male fetus with a postnatal autopsy finding of … On postnatal scan, in some children, no cystic renal tissue was seen, but there was an absence of renal tissue. 2007 Jul;37(4):249-60. doi: 10.1053/j.semnuclmed.2007.02.008.Exp Ther Med. OBJECTIVES: To establish the diagnostic accuracy of obstetric ultrasound at a tertiary fetal medicine center in the prenatal detection of unilateral and bilateral multicystic dysplastic kidney (MCDK) in fetuses in which this condition was suspected, and to undertake a systematic review of the relevant literature. Two reviewers (C.S., U.L.R.M.) Medknow Publications and Media Pvt Ltd Conclusions: The prevalence of different types of CAKUT is higher than that reported in developed countries. In the patients managed conservatively, 38% underwent no resolution on sequential ultrasonograms during the 2‐year follow‐up, and in four children, where complete resolution of the MCRD had occurred on ultrasonography, significant cellular renal masses were excised at subsequent surgery.Conclusion Patients with MCRD have significant associated urological malformations and the natural history in such patients is unpredictable. This information was gathered by reviewing information in case notes, radiology databases and electronically recorded clinic letters, either in our hospital or in the referring unit. Nevertheless, we cannot exclude the possibility of missed diagnoses or referral bias contributing to this difference, though this is unlikely due to the structured referral pathways in the entire region for both fetal medicine and nephrology services.The strengths of our study are the large number of cases included, the detailed antenatal assessment in a specialist fetal medicine center and the use of a unified protocol for postnatal assessment. Diagnosis was confirmed by postnatal ultrasound reports or postmortem examination. Four patients developed impaired renal function during the course of observation and 10 patients required urological surgery for other pathologies. 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