Cerner Multum, Inc. "Australian Product Information." O 04. Spiriva (tiotropium)." Measures should be taken whenever possible to minimize ocular exposure to these drugs, such as keeping eyes closed during oral inhalation or use of a mouthpiece rather than face mask during nebulization. Cerner Multum, Inc. "UK Summary of Product Characteristics." Caution is recommended when prescribing this agent to patients with impaired liver function.Moderate Potential Hazard, Low plausibility. Erectile dysfunction (ED) is a condition in which you can’t get or maintain an erection hard enough for penetration or orgasm, even when you’re interested in sex. Applies to: ArrhythmiasCases of supraventricular tachycardia and atrial fibrillation have been reported with the use of inhaled anticholinergic agents in patients with COPD/Asthma. Applies to: Liver DiseaseThe effects of hepatic impairment on the pharmacokinetics of tiotropium have not been studied. Tiotropium is primarily eliminated unchanged by the kidney. Tiotropium (Includes Spiriva) ↔ renal dysfunction. Patients should be advised of and monitored for potentially increased systemic adverse effects such urinary retention.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. "Tiotropium (Spiriva) for COPD." "Product Information. "Product Information. Mild renal impairment (CrCl 50 to 80 mL/min), which is often seen in elderly patients, increased tiotropium systemic exposure (AUC) by 39% following intravenous infusion. I work four 12-hour days as a foreman at a gun factory, and am tired a lot of the time. Patients should be advised to contact their physician if they experience urinary difficulty (especially in patients with prostatic hyperplasia or bladder neck obstruction); or signs and symptoms of angle-closure glaucoma (e.g., eye pain or discomfort; blurred vision; visual halos; colored images in association with red eyes from conjunctival congestion or corneal edema).Moderate Potential Hazard, Moderate plausibility. Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L "Inhaled tiotropium bromide and risk of stroke." Some people may assume ED increases with age. It is not uncommon for men with erectile dysfunction (ED) to feel angry, frustrated, sad, or even unsure of themselves. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Accordingly, therapy with quaternary ammonium compounds should be administered cautiously in patients with urinary retention/obstruction or angle-closure glaucoma. Increased intraocular pressure and precipitation or exacerbation of angle-closure glaucoma may also occur due to inadvertent contact of the eye with aerosolized or nebulized drug. We comply with the HONcode standard for trustworthy health information - Although systemic effects are uncommon due to the poor absorption of quaternary ammonium compounds from gastrointestinal and nasal mucosa, worsening of urinary retention or angle-closure glaucoma has been reported. Erectile dysfunction (ED) is the inability to get or keep an erection firm enough to have sexual intercourse. Spiriva Respimat (tiotropium)." Erectile dysfunction (impotence) is the inability to get and keep an erection firm enough for sex.Having erection trouble from time to time isn't necessarily a cause for concern. 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