Give a list of all your medicines to any healthcare provider who treats you.Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. An Infection 4. Tell your doctor about all your medications and any you start or stop using during treatment with Zocor, especially:This list is not complete and many other drugs can interact with simvastatin. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.Never take Zocor in larger amounts, or for longer than recommended by your doctor. Don't stop taking your statin medication before talking to your doctor. Zocor (simvastatin) reduces low-density lipoprotein cholesterol and total cholesterol in the blood. Mayo Clinic does not endorse any of the third party products and services advertised.A single copy of these materials may be reprinted for noncommercial personal use only. Indigestion 11. Since they are over-the-counter medications, you will not have problems looking for one. We comply with the HONcode standard for trustworthy health information - Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Your doctor may need to change your treatment plan if you use certain antibiotics or antifungal medicines, hepatitis C medication, heart medication, or medicines to treat HIV/AIDS.You should not take Zocor if you are allergic to simvastatin, if you are pregnant or breast-feeding, or if you have active liver disease.The following drugs can increase your risk of serious muscle problems if you take them together with Zocor. I have been getting headaches more frequently, (not the brain fog from being glutened) What is the safest thing to take? Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; orliver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).cold symptoms such as stuffy nose, sneezing, sore throat.This is not a complete list of side effects and others may occur. You may report side effects to FDA at 1-800-FDA-1088.Many drugs can interact with simvastatin. Intense Abdominal Pain 12. Anyone else get frequent headaches? Constipation 5. Botulinum Toxin A: 1.12 12. While you won't need to eliminate grapefruit entirely from your diet, ask your doctor about how much grapefruit you can have.Some drugs that may interact with statins and increase your risk of side effects include:There are many drugs that may interact with statins, so be sure your doctor is aware of all the medicines you take when being prescribed with statins.To relieve side effects believed to be caused by statins, your doctor may recommend several options. Remember that statin medications can reduce your risk of a heart attack or stroke, and the risk of life-threatening side effects from statins is very low.If you have read about the potential side effects of statins, you may be more likely to blame your symptoms on the medication, whether or not they're truly caused by the drug.Even if your side effects are frustrating, don't stop taking your statin medication for any period of time without talking to your doctor first. failure. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins.Occasionally, statin use could cause an increase in the level of enzymes that signal liver inflammation. Herbal Hair Oil For Headaches: 1.14 14. Bronchitis 3. Not all possible interactions are listed here. Roll-on Oils To Treat Headaches: 1.15 15. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. A Skin Rash 3. Skip the missed dose if it is almost time for your next scheduled dose. If experienced, these tend to have a Severe expression 1. Talk to your doctor to see if a change of dosage or even a different type of medication might be helpful.One of the most common complaints of people taking statins is muscle pain. If the increase is only mild, you can continue to take the drug. Risk factors include:Grapefruit juice contains a chemical that can interfere with the enzymes that break down (metabolize) the statins in your digestive system.